170033-55-3 Usage
General Description
(R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is a chemical compound with the molecular formula C13H18N2O. It is a piperazinone derivative and belongs to the class of organic compounds known as N-alkylpiperazines. (R)-3-Methyl-1-(phenylmethyl)piperazin-2-one is often used in medicinal chemistry and pharmacology for its ability to modulate various neurotransmitter systems in the central nervous system. It has also been studied for its potential in the treatment of various neurological and psychiatric disorders. Additionally, (R)-3-Methyl-1-(phenylmethyl)piperazin-2-one has been investigated for its potential use as a building block in the synthesis of other pharmaceuticals and organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 170033-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,0,3 and 3 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 170033-55:
(8*1)+(7*7)+(6*0)+(5*0)+(4*3)+(3*3)+(2*5)+(1*5)=93
93 % 10 = 3
So 170033-55-3 is a valid CAS Registry Number.
170033-55-3Relevant articles and documents
Asymmetric Synthesis of 2,6-Methylated Piperazines
Mickelson, John W.,Belonga, Kenneth L.,Jacobsen, Jon E.
, p. 4177 - 4183 (2007/10/02)
The complete series of enantiopure 2,6-methylated piperazines was synthesized utilizing two alternative reactions in the key bond-forming step.The dimethyl enantiomers, (2R,6R)- and (2S,6S)-2,6-dimethylpiperazine (1, 2), were prepared using either a diastereoselective triflate alkylation or a novel intermolecular Mitsunobu reaction to set the required stereochemistry.The monomethyl derivatives, (R)- and (S)-tert-butyl 2-methyl-1-piperazinecarboxylate (3, 4) were also synthesized employing the Mitsunobu cyclization strategy while the trimethyl compounds, (R)- and (S)-2,2,6- trimethylpiperazine (5, 6) were prepared using an enantiospecific triflate alkylation as the principal reaction.These methods represent efficient, general strategies for preparing a variety of 2,6-methylated piperazines for which the absolute stereochemistry can be readily controlled.
