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17016-89-6

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17016-89-6 Usage

Description

L-Valinol hydrochloride, a derivative of the amino acid L-valine, is a chemical compound that serves as a chiral building block in organic synthesis. It is recognized for its potential in creating chiral catalysts for asymmetric synthesis, making it a versatile and important chemical reagent in the field of organic chemistry due to its chiral nature and the ability to facilitate enantioselective reactions.

Uses

Used in Pharmaceutical Industry:
L-Valinol hydrochloride is used as a chiral building block for the synthesis of various pharmaceuticals. Its chiral nature allows for the creation of enantioselective reactions, which is crucial in producing drugs with specific biological activities and minimizing side effects.
Used in Agrochemical Industry:
In the agrochemical industry, L-Valinol hydrochloride is utilized as a chiral building block in the development of agrochemicals. Its ability to participate in enantioselective reactions contributes to the synthesis of effective and targeted agrochemicals with reduced environmental impact.
Used in Catalyst Development:
L-Valinol hydrochloride is used as a precursor in the development of chiral catalysts for asymmetric synthesis. These catalysts are essential in organic chemistry for producing enantiomerically pure compounds, which are vital in various applications, including pharmaceuticals and fragrances.

Check Digit Verification of cas no

The CAS Registry Mumber 17016-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,0,1 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 17016-89:
(7*1)+(6*7)+(5*0)+(4*1)+(3*6)+(2*8)+(1*9)=96
96 % 10 = 6
So 17016-89-6 is a valid CAS Registry Number.

17016-89-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-amino-3-methylbutan-1-ol,hydrochloride

1.2 Other means of identification

Product number -
Other names L-valinol hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17016-89-6 SDS

17016-89-6Downstream Products

17016-89-6Relevant articles and documents

Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate

Zhang, Yong-Kang,Plattner, Jacob J.,Easom, Eric E.,Jacobs, Robert T.,Guo, Denghui,Freund, Yvonne R.,Berry, Pamela,Ciaravino, Vic,Erve, John C. L.,Rosenthal, Philip J.,Campo, Brice,Gamo, Francisco-Javier,Sanz, Laura M.,Cao, Jianxin

, p. 5889 - 5908 (2017/07/22)

Carboxamide pyrazinyloxy benzoxaboroles were investigated with the goal to identify a molecule with satisfactory antimalarial activity, physicochemical properties, pharmacokinetic profile, in vivo efficacy, and safety profile. This optimization effort discovered 46, which met our target candidate profile. Compound 46 had excellent activity against cultured Plasmodium falciparum, and in vivo against P. falciparum and P. berghei in infected mice. It exhibited good PK properties in mice, rats, and dogs. It was highly active against the other 11 P. falciparum strains, which are mostly resistant to chloroquine and pyrimethamine. The rapid parasite in vitro reduction and in vivo parasite clearance profile of 46 were similar to those of artemisinin and chloroquine, two rapid-acting antimalarials. It was nongenotoxic in an Ames assay, an in vitro micronucleus assay, and an in vivo rat micronucleus assay when dosed orally up to 2000 mg/kg. The combined properties of this novel benzoxaborole support its progression to preclinical development.

Synthesis of L-prolyl-leucyl-α-aminoisobutyryl-α-amino-isobutyryl-glutamyl-valinol and proof of identity with the isolated C-terminal fragment of trichotoxin A-40

Bruckner,Jung

, p. 1677 - 1699 (2007/10/02)

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