170211-03-7

Usage

Uses

Used in Pharmaceutical Synthesis:
BDMP serves as a crucial building block in the creation of various pharmaceutical compounds. Its unique structure and properties allow it to be incorporated into a range of medicinal agents, contributing to the development of new drugs and therapeutics.
Used in Organic Synthesis:
As a versatile component in organic synthesis, BDMP is utilized to construct a variety of organic molecules. Its reactivity and structural features make it a valuable intermediate in the synthesis of complex organic compounds.
Used in Coordination Chemistry:
BDMP's potential as a ligand in coordination chemistry makes it a candidate for use in the formation of metal complexes. These complexes can have applications in areas such as catalysis, materials science, and medicinal chemistry.
Used in Organic Chemistry Reactions:
BDMP functions as a reagent in various organic chemistry reactions, facilitating the synthesis of target molecules and aiding in the advancement of organic chemistry methodologies.

InChI:InChI=1/C13H20N2/c1-11-8-15(9-12(2)14-11)10-13-6-4-3-5-7-13/h3-7,11-12,14H,8-10H2,1-2H3/t11-,12-/m1/s1

Upstream product

• 170211-02-6 (3S,5S)-3,5-Dimethyl-1-(phenylmethyl)piperazin-2-one 
• 170033-52-0 (S)-N-<2--1-methylethyl>-L-alanine methyl ester 
• 170033-51-9 (S)-2-Amino-1-propane 
• 170033-63-3 (S)-2-Amino-N,N-dibenzyl-propionamide 
• 170033-50-8 (S)-<2--1-methyl-2-oxoethyl>carbamic acid 1,1-dimethylethyl ester 
• 103-49-1 dibenzylamine 
• 162150-51-8 (R)-<2--1-methyl-2-oxoethyl>carbamic acid 1,1-dimethylethyl ester 
• 162150-52-9 (R)-N-<2--1-methylethyl>-D-alanine methyl ester 
• 674792-11-1 (R)-2-Amino-N,N-dibenzyl-propionamide 
• 74474-93-4 (R)-2-Amino-1-propane 
• 162240-92-8 (3R,5R)-3,5-Dimethyl-1-(phenylmethyl)piperazin-2-on 

Downstream Products

• 768335-42-8 (2R,6R)-2,6-dimethylpiperazine 
• 402832-69-3 (2S,6S)-2,6-dimethyl-piperazine 
• 956468-17-0 (2R,6R)-2,6-dimethylpiperazine hydrochloride 

Relevant academic research and scientific papers

QUINOLINE DERIVATIVES AS SMO INHIBITORS

Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Compound 1 shows anti-obesity efficacy without potentiating erectile activity in the rodent models.

PIPERAZINE UREA DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS

Certain novel piperazine urea derivatives are agonists of the human melanocortin-4 receptor (MC-4R) and, in particular, are receptor-subtype selective agonists of MC-4R. They are useful for the treatment, control, or prevention of diseases and disorders r

Asymmetric Synthesis of 2,6-Methylated Piperazines

The complete series of enantiopure 2,6-methylated piperazines was synthesized utilizing two alternative reactions in the key bond-forming step.The dimethyl enantiomers, (2R,6R)- and (2S,6S)-2,6-dimethylpiperazine (1, 2), were prepared using either a diastereoselective triflate alkylation or a novel intermolecular Mitsunobu reaction to set the required stereochemistry.The monomethyl derivatives, (R)- and (S)-tert-butyl 2-methyl-1-piperazinecarboxylate (3, 4) were also synthesized employing the Mitsunobu cyclization strategy while the trimethyl compounds, (R)- and (S)-2,2,6- trimethylpiperazine (5, 6) were prepared using an enantiospecific triflate alkylation as the principal reaction.These methods represent efficient, general strategies for preparing a variety of 2,6-methylated piperazines for which the absolute stereochemistry can be readily controlled.

Asymmetric Synthesis of (2R,6R) and (2S,6S)-2,6-Dimethylpiperazine

The title compounds were prepared via two efficient routes.The first sequence utilized a diastereospecific triflate alkylation in the key bond forming step while the second method relied on a novel intramolecular Mitsunobu reaction to set the required stereochemistry.