170230-23-6

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-bromophenyl)-1H-1,2,4-triazole is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical properties and structural features.
Used in Antifungal Applications:
1-(4-bromophenyl)-1H-1,2,4-triazole is used as an antifungal agent, leveraging its biological activities to combat fungal infections.
Used in Antitumor Applications:
1-(4-bromophenyl)-1H-1,2,4-triazole is used as an antitumor agent, with potential benefits in the treatment of cancer due to its biological activities and interactions with cellular processes.

Upstream product

• 67-56-1 methanol 
• 50-00-0 formaldehyd 
• 589-21-9 (4-bromophenyl)hydrazine 
• 589-87-7 1,4-bromoiodobenzene 
• 288-88-0 1,2,4-Triazole 
• 77287-34-4 formamide 

Downstream Products

• 1384951-86-3 1-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenyl]-1H-[1,2,4]triazole 
• 1101873-48-6 1-(4-(1H-1,2,4-triazol-1-yl)phenyl)-4-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one 
• 1394373-90-0 (3R,3aR,6R,6aR)-6-[6-chloro-5-[4-[4-(1,2,4-triazol-1-yl)phenyl]phenyl]-1-(2-trimethylsilylethoxymethyl)imidazo[4,5-b]pyridin-2-yl]oxy-2,3,3a,5,6,6a-hexalydrofuro[3,2-b]furan-3-ol 

Relevant academic research and scientific papers

Asymmetric antracene derivatives having two phenyl groups and organic light-emitting diode including the same

The present invention relates to an antracene derivative represented by [Chemical Formula A] and an organic light-emitting diode including the same, wherein substituents X_1 to X_5, Y, and Z are the same as defined in the detailed description of the invention. [Chemical Formula A].

AMPK ACTIVATORS

This disclosure is directed, at least in part, to AMPK activators useful for the treatment of conditions or disorders associated with AMPK. In some embodiments, the condition or disorder is associated with the gut-brain axis. In some embodiments, condition or disorder is associated with systemic infection and inflammation from having a leaky gut barrier. In some embodiments, the AMPK activators are gut-restricted compounds. In some embodiments, the AMPK activators are agonists or partial agonists.

Antracene derivatives having heteroaryl substituted phenyl group and organic light-emitting diode including the same

The present invention relates to an anthracene derivative represented by Chemical Formula A and an organic light-emitting device including the same, wherein substituents X1 to X5, Y, and Z are the same as defined in detailed explanation of the invention.

Antracene derivatives having heteroaryl substituted phenyl group and organic light-emitting diode including the same

The present invention relates to an antracene derivative represented by the following [Formula A] and an organic light-emitting diode including the same. Z , Y, and L are the same as defined in the detailed description of the invention.

A Multicomponent Electrosynthesis of 1,5-Disubstituted and 1-Aryl 1,2,4-Triazoles

A novel electrochemical route has been developed for the synthesis of 1,5-disubstituted and 1-aryl 1,2,4-triazoles from aryl hydrazines, paraformaldehyde, NH4OAc, and alcohols. In this multicomponent reaction system, alcohols act as solvents as well as reactants and NH4OAc is used as the nitrogen source. With the assistance of reactive iodide radical or I2 and NH3 electrogenerated in situ, this process could effectively avoid the use of strong oxidants and transition-metal catalysts and be smoothly carried out at room temperature to give a wide array of 1,2,4-triazole derivatives in good to high yields. Preliminary studies reveal that the reaction mechanism involves a radical process.

CATHEPSIN K INHIBITOR AND APPLICATION THEREOF

The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.

Magnetically recoverable copper nanorods and their catalytic activity in Ullmann cross-coupling reaction

A novel polydentate ligand supported on Fe3O4@SiO2 was designed and demonstrated for the synthesis of Cu nanorods. The Fe3O4@SiO2/EP.EN.EG@Cu was characterized using X-ray diffraction, ther

Organic light-emitting diode including aryl substituted antracene derivatives

The present invention, in regards to an organic light emitting diode comprising a luminous layer and an electron transport layer between a first electrode and a second electrode, relates to an organic light emitting diode which includes one or more anthracene derivatives selected from compounds represented by chemical formula A below in the electron transport layer, and which includes one or more anthracene derivatives selected from compounds represented by chemical formula B below in the luminous layer. L_a, L_b, A, Y and m below are defined in the detailed description of the present invention.

Organic light-emitting diode including aryl substituted antracene derivatives

The present invention, in regards to an organic light-emitting diode comprising a luminous layer and an electron transport layer between a first electrode and a second electrode, relates to an organic light emitting diode which includes one or more anthracene derivatives selected from compounds represented by chemical formula A below in the electron transport layer, and which includes one or more anthracene derivatives selected from compounds represented by chemical formula B below in the luminous layer. L_1, L_2, Y, Z, m, and m′ below are defined in the detailed description of the present invention.

Microwave-assisted catalyst-free synthesis of substituted 1,2,4-triazoles

A simple, efficient, and mild method has been developed for the synthesis of substituted 1,2,4-triazoles from hydrazines and formamide under microwave irradiation. The reaction proceeds smoothly in the absence of a catalyst and shows excellent functional-group tolerance.