170242-34-9

Usage

Uses

Used in Pharmaceutical Research and Development:
2-AMINO-5-[1,3]DIOXOLAN-2-YL-PENTANOIC ACID is used as a key building block for the synthesis of potential pharmaceutical drugs. Its unique structure allows it to be incorporated into various drug candidates, potentially leading to the discovery of new treatments for a range of medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 2-AMINO-5-[1,3]DIOXOLAN-2-YL-PENTANOIC ACID is used as a versatile intermediate. Its dioxolane ring and amino group provide opportunities for further chemical reactions, making it a valuable component in the creation of new chemical entities for a variety of applications.
Used in Industrial Applications:
2-AMINO-5-[1,3]DIOXOLAN-2-YL-PENTANOIC ACID is also utilized in various industrial applications. Its properties make it suitable for use in the development of new chemicals and materials, contributing to advancements in different sectors such as materials science, agriculture, and environmental technology.

InChI:InChI=1/C8H15NO4/c9-6(8(10)11)2-1-3-7-12-4-5-13-7/h6-7H,1-5,9H2,(H,10,11)

Upstream product

• 226725-71-9 N-benzoyl allysine ethylene acetal 
• 16776-90-2 5-(1,3-dioxolan-2-yl)-1-pentanal 

Downstream Products

• 189952-46-3 (2S,5R)-methyl 5-hydroxypiperidine-2-carboxylate 

Relevant academic research and scientific papers

The combination of hydroformylation and biocatalysis for the large-scale synthesis of (S)-allysine ethylene acetal

The compound, (S)-2-amino-5-[1,3]dioxolan-2-yl-pentanoic acid [(S)-allysine ethylene acetal], is a key intermediate in a number of angiotension-I converting enzyme (ACE) and neutral endopeptidase (NEP) inhibitors currently in clinical trials. Through a co

Process for producing L-allysine acetals

The present invention has for its object to provide a method for producing an L-allysine acetal which involves a fewer steps and is efficient. This invention relates to method for producing an L-allysine acetal which comprises; converting a D,L-allysine acetal of the following general formula (1) (wherein R1and R2are the same or different, and each of them represents an alkyl group having 1 to 8 carbon atoms, or they combinedly form a ring and represent an alkylene group having 2 to 8 carbon atoms) to a mixture of a 2-oxo-6,6-dialkoxyhexanoic acid of the following general formula (2) (wherein R1and R2are as defined above) and an L-allysine acetal of the following general formula (3) (wherein R1and R2are as defined above) by reacting in the presence of an enzyme capable of stereoselective oxidative deamination of D-amino acids and; isolating said L-allysine acetal after said converting.

Method for producing L-Allysine acetal

A method for producing L-allysine acetal represented by general formula (II), comprising reacting D,L-allysinamide acetal represented by general formula (I) with cells of microorganism or treated cell product having an activity of stereoselectively hydrolyzing L-allysinamide acetal, wherein R1and R2, which may be the same or different, each independently represent a lower alkyl group, or R1and R2are combined to form an alkylene group represented by [CH2]n, and n is 2 to 3. D,L-allysinamide acetal represented by general formula (I) is also in the scope of the invention. According to the present invention, L-allysine acetal useful as a raw material for medicine can be produced in a smaller number of steps at low costs.