189952-46-3

Basic information

• Product Name: 2-Piperidinecarboxylicacid,5-hydroxy-,methylester,cis-(9CI)
• Synonyms: 2-Piperidinecarboxylicacid,5-hydroxy-,methylester,cis-(9CI)
• CAS NO: 189952-46-3
• Molecular Formula: C7H13NO3
• Molecular Weight: 0
• Product Categories: CARBOXYLICESTER
• Mol File: 189952-46-3.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Piperidinecarboxylicacid,5-hydroxy-,methylester,cis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinecarboxylicacid,5-hydroxy-,methylester,cis-(9CI)(189952-46-3)
• EPA Substance Registry System: 2-Piperidinecarboxylicacid,5-hydroxy-,methylester,cis-(9CI)(189952-46-3)

Safety Data

• Hazardous Substances Data: 189952-46-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 13096-31-6 5-hydroxypiperidine-2-carboxylic acid 
• 15069-92-8 5-hydroxypicolinic acid 
• 50439-45-7 (2S,5R)-5-hydroxy-2-piperidinecarboxylic acid 
• 215054-80-1 (S)-2-amino-5-(1,3-dioxolane-2-yl)-pentanoic acid 
• 852822-01-6 (S)-2-Benzyloxycarbonylamino-5-[1,3]dioxolan-2-yl-pentanoic acid 
• 824943-43-3 (S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester 
• 227758-97-6 (2S)-3,4-dihydro-2H-pyridine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 824943-45-5 (2S,5R)-5-hydroxy-6-methoxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 448964-01-0 (2R,5R)-5-hydroxypiperidine-2-carboxylic acid 
• 26566-11-0 N-(benzyloxycarbonyl)-D-glutamic acid 1-methyl ester 
• 97975-57-0 (4R)-4-(2-Carboxyethyl)-3-[(phenylmethoxy)carbonyl]oxazolidin-5-one 
• 63648-73-7 N-benzyloxycarbonyl-D-glutamic acid 
• 6893-26-1 D-Glutamic acid 

Downstream Products

• 1463501-46-3 (2S,5R)-5-(benzyloxyamino)piperidin-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 

Relevant articles and documents

Five-membered heteroaromatic derivative, preparation method and application thereof

The invention belongs to the technical field of medicines, and particularly relates to a five-membered heteroaromatic compound, a composition, a preparation method and application thereof. The compound or the composition can be used as an inhibitor of a retinoid-related orphan receptor [gamma]t (ROR [gamma]t). The invention also relates to a method for preparing the compound and the composition, and application of the compound and the composition in treatment or prevention of ROR [gamma]t-mediated cancers, inflammations or autoimmune diseases of mammals, especially human beings.

THERAPEUTIC METHODS

The invention provides methods and compositions for delivering a nucleic acid to a cell or the cytosol of the target cell. The method includes contacting the cell with, 1) a membrane-destabilizing polymer; and 2) a nucleic acid conjugate. The nucleic acid conjugate includes a targeting ligand bound to an optional linker and a nucleic acid.

METHODS FOR TREATING HEPATITIS B INFECTIONS

Certain embodiments of the invention provide a method for identifying a patient that has a higher likelihood of responding to an HBV antigen inhibitor, such a method comprising detecting a hepatitis B virus (HBV) infected patient's genotype at one or more of the IL28B/A associated SNPs described herein, wherein the relevant genotype(s) described herein are indicative of a patient that has a higher likelihood of responding to an HBV antigen inhibitor as compared to an HBV infected patient having different genotypes at these locations.