170303-33-0

Usage

Structure

pentylamine backbone with a phenylseleno group attached

Derivative

amino acid lysine

Usage

organic synthesis, building block for pharmaceuticals and other chemical compounds

Potential applications

medicinal chemistry, drug development, biological and pharmacological activities

Utility

reagent in chemical reactions

Versatility

potential applications in various industries and scientific fields

Upstream product

• 5414-21-1 5-bromopentan-1-nitrile 
• 1666-13-3 diphenyl diselenide 
• 170303-51-2 5-benzeneselenyl-1-pentanonitrile 

Downstream Products

• 651294-31-4 2-{[5-(phenylselanyl)pentyl]amino}propanenitrile 
• 595581-92-3 5-chloro-6-methyl-3-phenyl-1-[5-(phenylselanyl)pentyl]-2(1H)-pyrazinone 
• 595581-91-2 3,5-dichloro-6-methyl-1-[6-(phenylselenyl)pentyl]-2(1H)-pyrazinone 
• 595581-93-4 5-chloro-6-methyl-1-(4-pentenyl)-3-phenyl-2(1H)-pyrazinone 

Relevant academic research and scientific papers

Radical cyclisations of imines and hydrazones

Radical cyclisation of sp3 carbon-centred radicals onto imines and hydrazones provides a new method for the synthesis of 5- and 6-membered ring nitrogen heterocycles. Cyclisation onto the electrophilic carbon of the C=N group and 5-exo stereoelectronic selectivity are the dominating mechanistic parameters. The C-centred radical intermediates were generated from benzeneselenyl precursors using Bu3SnH.

Cyclisation of Carbinyl Radicals onto Imines and Hydrazones

The regioselectivity of intramolecular addition of sp3 carbon-centered radicals onto C=N double bonds of imines and hydrazones is influenced by the position and polarisation of the C=N bond.