170304-83-3

Usage

Uses

3-Benzylpyrrolidine is a useful reactant in organic synthesis.

InChI:InChI=1/C11H15N/c1-2-4-10(5-3-1)8-11-6-7-12-9-11/h1-5,11-12H,6-9H2

Upstream product

• 66195-04-8 3-benzyl-pyrrolidine-2,5-dione 
• 86553-38-0 1-[(4-methylphenyl)sulfonyl]-2-benzylpyrrolidine 
• 14063-01-5 3-benzylidenepyrrolidin-2,5-dione 
• 100-52-7 benzaldehyde 

Downstream Products

• 1258502-29-2 3-benzyl-N-(2-(5-chloro-1H-indol-3-yl)ethyl)pyrrolidine-1-carboxamide 
• 1121728-65-1 MMV₆₅₉₀₀₄ 
• 1308375-70-3 3-((R)-2-amino-2-phenyl-ethyl)-5-(3-benzyl-pyrrolidin-1-yl)-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 
• 1602923-66-9 (4-chlorophenyl)-carbamic acid (S)-1-(3-benzylpyrrolidin-1-ylmethyl)-2,2,2-trifluoro-ethyl ester 
• 1602924-20-8 (2S)-3-(3-benzylpyrrolidin-1-yl)-1,1,1-trifluoropropan-2-ol 
• 1373952-52-3 C₃₈H₃₄N₆O₂ 
• 288082-49-5 C₃₀H₃₄N₆O₃ 
• 613676-60-1 5-[(3-benzyl-1-pyrrolidinyl)carbonyl]-2-methylpyridine 

Relevant academic research and scientific papers

Ni-catalyzed two-component reductive dicarbofunctionalization of alkenes via radical cyclization

A reductive dicarbofunctionalization reaction of alkenes has been developed and applied to the preparation of substituted carbo- and heterocycles. The reaction conditions avoid the use of air-sensitive organometallic reagents, and are compatible with a broad range of bromo-electrophiles and a wide variety of substituents to give cyclic products in excellent yields.

4-[ω-(tetralin-1-yl)alkyl]-1-benzylpiperazines and related compounds as 5-HT1A/D-2 ligands

N-Benzylpiperazine and -piperidine derivatives of long-chain piperazine were synthesized in order to obtain putative atypical antipsychotic agents with a dual 5-HT1A/D-2 affinity and reduced, or without, α1 adrenergic affinity. The 5-HT1A/D-2/α1 receptor binding results show that only compound 30, 2-(2-methoxybenzyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)-n-propyl] piperazine, has an acceptable binding affinity profile (pKi= 7.9, 7.1, 6.7, respectively).