170355-38-1

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 5-bromothiophene-3-carboxylate is utilized as a building block for the development of pharmaceuticals. Its ability to participate in various chemical reactions to form new carbon-carbon and carbon-heteroatom bonds makes it a valuable starting material for the synthesis of complex organic molecules with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, Ethyl 5-bromothiophene-3-carboxylate serves as a key intermediate in the synthesis of various agrochemicals. Its reactivity and structural features contribute to the creation of compounds with pesticidal or herbicidal properties, enhancing crop protection strategies.
Used in Organic Synthesis:
Ethyl 5-bromothiophene-3-carboxylate is employed as a versatile starting material in organic synthesis. Its capacity to engage in multiple types of chemical reactions allows for the construction of a wide array of organic compounds, which can be further utilized in various chemical and material science applications.
Used in Antimicrobial and Anti-fungal Applications:
Ethyl 5-bromothiophene-3-carboxylate has been studied for its potential biological activity, particularly its antimicrobial and antifungal properties. This makes it a candidate for use in applications where resistance to common antibiotics or antifungals is a concern, offering an alternative or adjunct to existing treatments.

InChI:InChI=1/C7H7BrO2S/c1-2-10-7(9)5-3-6(8)11-4-5/h3-4H,2H2,1H3

Upstream product

• 100523-84-0 2-bromothiophene-4-carboxylic acid 
• 71-23-8 propan-1-ol 
• 64-17-5 ethanol 

Downstream Products

• 960116-27-2 ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxylate 
• 100523-84-0 2-bromothiophene-4-carboxylic acid 
• 1174718-25-2 5-(3,5-dichlorophenyl)-3-thiophene carboxylic acid ethyl ester 
• 1278405-37-0 (S)-ethyl 4-(1-(tert-butoxycarbonyl)piperidin-3-ylamino)-2-(3-fluorophenyl)thieno[2,3-d]pyridazine-7-carboxylate 
• 1174718-12-7 C₂₃H₂₅ClN₄O₃S 
• 1174718-11-6 C₂₅H₂₈ClN₃O₄S 
• 1278405-38-1 (S)-tert-butyl 3-(7-carbamoyl-2-(3-fluorophenyl)thieno[2,3-d]pyridazin-4-ylamino)piperidine-1-carboxylate 

Relevant academic research and scientific papers

A Stable Blue Photosensitizer for Color Palette of Dye-Sensitized Solar Cells Reaching 12.6% Efficiency

We report a blue dye, coded as R6, which features a polycyclic aromatic hydrocarbon, 9,19-dihydrobenzo[1′,10′]phenanthro[3′,4′:4,5]thieno[3,2-b]benzo[1,10]phenanthro[3,4-d]thiophene, coupled with a diarylamine electron donor and 4-(7-ethynylbenzo[c][1,2,5]thiadiazol-4-yl)benzoic acid acceptor. Dye R6 displays a brilliant sapphire color in a sensitized TiO2 mesoporous film with a Co(II/III) tris(bipyridyl)-based redox electrolyte. The R6 based dye-sensitized solar cell achieves an impressive power conversion efficiency of 12.6% under standard air mass 1.5 global, 100 mW cm-2, and shows a remarkable photostability.

Anthracene-based fused ring aromatic hydrocarbon organic dye and preparation method thereof

The invention relates to the field of dye-sensitized solar cells, and aims to provide an anthracene-based fused ring aromatic hydrocarbon organic dye and a preparation method thereof. The molecular structural formula of the organic dye is as shown in the formula (I). The anthracene-based fused ring aromatic hydrocarbon organic dye is used for modifying an auxiliary electron donor D and an electronacceptor A on constructed anthracene-based fused ring aromatic hydrocarbon, so that when the organic dye prepared through the preparation method is applied to the dye-sensitized solar cells, the photoelectric conversion efficiency is high; the raw materials of the organic dye are wide in source, the cost is low, the preparation method is simple, and industrial production can be achieved. The molecular structural formula (I) is shown in the description.

THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES

The present invention relates to thienopyridazine compounds of formula (I), their pharmaceutically acceptable salts or hydrates, wherein R1 and R2 are independently H or C1-4 alkyl, R3 is a saturated or unsaturated 5- or 6- membered ring containing N, S or O, or its optical isomers, R4 is a halophenyl monosubstituted or disubstituted at any position. The present invention provides the preparation methods of these compounds, pharmaceutical compositions containing these compounds and the uses of these compounds, particularly in treating cancer.

Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition

Novel compound having the following formula: Also disclosed are a pharmaceutical compositions comprising the same, methods for treating cancer using the same, and methods for the synthesis of the same. The novel compounds of the present invention are found to inhibit protein kinases, especially Checkpoint kinase Chk1/Chk2.