170377-20-5Relevant academic research and scientific papers
The Reaction of Carbon Disulfide with Diethyl 3-Amino-2-cyano-2-penten-1,5-dicarboxylate: A Convenient Synthesis of Polyfunctionally Substituted Thiophenes andd Their Fused Derivatives
Sherif, S. M.,Abdel-Sayed, N. I.,El-Kousy, S. M.,Mohareb, R. M.
, p. 601 - 608 (2007/10/02)
Carbon disulfide added to the active methylene group in 1 in basic DMF at room temperature to yield the non-isolable 1:1 adduct 2.In-situ cyclization of the latter with some α-bromo compounds afforded the corresponding polyfunctionally substituted thiophenes 5.The reactivity of 5 towards a variety of reagents was studied.Chemical and spectroscopic evidences for the structure of the new compounds are provided.Keywords: Thiophene; Thienodipyrazole; Thienopyrazole
