170379-98-3Relevant academic research and scientific papers
Chiral diselenides in the total synthesis of (+)-samin
Wirth, Thomas,Kulicke, Klaus J.,Fragale, Gianfranco
, p. 2686 - 2689 (1996)
Chiral selenium compounds are applied to stoichiometric as well as to catalytic reactions in the synthesis of substituted tetrahydrofuran derivatives: The selenium compound 1 was used in catalytic amounts for a rapid access to chiral diselenide 3. The efficient stereoselective addition to alkene 5 yields product 8 with a selenium functionality as a precursor for an intramolecular radical cyclization. In this way a short total synthesis of (+)-samin (11), a naturally occurring furofuran lignan, was achieved.
Asymmetrische Umsetzung von Arylalkenen mit Diseleniden
Wirth, Thomas
, p. 1872 - 1873 (2007/10/03)
Stichworte: Arylalkene; Asymmetrische Synthesen; Chirale Diselenide; Selenverbindungen
