17038-88-9

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 62-53-3 aniline 

Downstream Products

• 653603-82-8 3-[phenyl-(1-trimethylsilanyl-ethyl)-amino]-propionic acid tert-butyl ester 
• 653603-85-1 3-[phenyl-(1-triethylsilanyl-ethyl)-amino]-propionic acid tert-butyl ester 
• 144024-06-6 1,1-Dimethylethyl 2,5-dihydro-4-hydroxy-5-oxo-1-phenyl-1H-pyrrole-3-carboxylate 
• 62-53-3 aniline 
• 91904-57-3 N,N-diethyl-3-phenylaminopropionamide 
• 959996-02-2 C₁₈H₁₇ClN₂O₃S 
• 959995-86-9 1-(4-Chlorophenylsulfonyl)-2,3-dihydroquinolin-4(1H)-one 
• 92426-15-8 (4-chloro-N-phenylphensulfonamido)propanoic acid 
• 1190853-65-6 5-(4-chlorophenylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline 
• 1431327-96-6 tert-butyl 3-(N-phenylacetamido)propanoate 
• 653603-89-5 3-[(4-formyl-phenyl)-(1-triethylsilanyl-ethyl)-amino]-propionic acid tert-butyl ester 
• 653603-86-2 3-[(4-formyl-phenyl)-(1-trimethylsilanyl-ethyl)-amino]-propionic acid tert-butyl ester 

Relevant academic research and scientific papers

Aminosilanes as two-electron donors: A technological application of radical cation chemistry

Aminosilanes possess the appropriate structural features for use as two-electron sensitizers in silver halide photography. Here, we describe studies of the nucleophile-assisted cleavage reactions of the C - Si bonds in their radical cations. Water is identified as a useful nucleophile. It is found that the kinetics of these reactions are best described by taking into account a radical cation - water complex. The cleavage reactions are also controlled by steric effects at silicon and by the proximity of a carboxylate group that can modify the nucleophilicity of the water. Cleavage forms an α-amino radical that can donate a second electron to 9,10-dicyanoanthracene as a solution-phase electron acceptor.

Method for catalyzing amino protection by imidazole hydrochloride

The invention provides an amino protection method which realizes multi-substituted amino protection by using imidazole hydrochloric acid as an accelerator to push derivatives of primary amine, secondary amine and acrylamide to perform Michael addition at a relatively low temperature, wherein the imidazole hydrochloric acid promotes a carbon-nitrogen bond to crack back to the derivatives of primaryamine and acrylamide at a high temperature. The method provided by the invention is simple and economical, high in practicability, free of any other catalysts or additives, capable of protecting amino to have good functional group tolerance and excellent yield and purity, short in reaction time, free from harsh reaction conditions and suitable for industrial production.

Michael addition reaction catalyzed by imidazolium chloride to protect amino groups and construct medium ring heterocycles

An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.

Cis -trans amide bond rotamers in β-peptoids and peptoids: Evaluation of stereoelectronic effects in backbone and side chains

Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but h

Towards the synthesis of aminodibenzo[b,e][1,4]dioxin derivatives via cationic ruthenium complexes

Double nucleophilic aromatic substitution reactions between N-substituted (η6-1,2-dichlorobenzene)RuCp+ salts and substituted 1,2-benzenediols have been carried out under mild conditions to prepare N-substituted (η6-dibenzo[b,e][1,4]dioxin)ruthenium(II) complexes. The dibenzodioxin ligands were subsequently liberated by photolysis, with radiation from a sunlamp or from a medium pressure Hg lamp (300 nm).

N-substituted lactams useful as cholecystokinin antagonists

This invention relates to novel N-substituted lactams having the following formula STR1 useful in the treatment and prevention of Cholecystokinin (CCK) related disorders of the gastrointestinal, central nervous and appetite regulatory systems of mammals.