170452-98-9Relevant articles and documents
A simple approach to 1',1'-a-methano carbocyclic thymidine
Ezzitouni,Barchi Jr.,Marquez
, p. 1345 - 1346 (1995)
An enantioselective synthesis of 1',1'a-methano carbocyclic thymidine, a rigid molecule that mimics thymidine's 2'-endo/3'-exo (South) conformation, is efficiently synthesized from chiral 2-benzyloxymethylcyclopent-3-enol.
Conformationally locked carbocyclic nucleosides built on a bicyclo[3.1.0]hexane template with a fixed Southern conformation. Synthesis and antiviral activity
Ezzitouni, Abdallah,Marquez, Victor E.
, p. 1073 - 1078 (2007/10/03)
The construction of carbocyclic nucleosides with a fixed 3E ring pucker in the Southern hemisphere of the pseudorotational cycle is achieved from a common precursor carbocyclic amine, (1S,3S,4R,5S)-3-benzyloxy-4-benzyloxymethyl-1-aminobicyclo[3