17046-23-0

Basic information

• Product Name: (S)-(-)-2-isocyanatoglutaric acid diethyl ester
• Synonyms: diethyl 2-isocyanatopentanedioate;2-Isocyanatopentanedioic acid diethyl ester
• CAS NO: 17046-23-0
• Molecular Formula: C₁₀H₁₅NO₅
• Molecular Weight: 229.23
• Mol File: 17046-23-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 289.3 °C at 760 mmHg
• Flash Point: 114 °C
• Appearance: /
• Density: 1.13
• Vapor Pressure: 0.00221mmHg at 25°C
• Refractive Index: 1.474
• CAS DataBase Reference: (S)-(-)-2-isocyanatoglutaric acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-2-isocyanatoglutaric acid diethyl ester(17046-23-0)
• EPA Substance Registry System: (S)-(-)-2-isocyanatoglutaric acid diethyl ester(17046-23-0)

Safety Data

• Hazardous Substances Data: 17046-23-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 2507, 1961 DOI: 10.1021/jo01351a088

InChI:InChI=1/C10H15NO5/c1-3-15-9(13)6-5-8(11-7-12)10(14)16-4-2/h8H,3-6H2,1-2H3

Upstream product

• 55895-85-7 diethyl 2-aminopentanedioate 

Downstream Products

• 96846-34-3 N-<<<2-carboxy-2-<<4-<<(2,4-diamino-6-pteridinyl)methyl>methylamino>benzoyl>amino>ethyl>amino>carbonyl>-L-glutamic acid 
• 96846-33-2 2-[3-((S)-3-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-3-ethoxycarbonyl-propyl)-ureido]-pentanedioic acid diethyl ester 
• 96846-32-1 2-[3-((S)-2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-2-ethoxycarbonyl-ethyl)-ureido]-pentanedioic acid diethyl ester 

Relevant articles and documents

METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE

The present invention provides a method for producing a carbamate that includes a step (1) and a step (2) described below: (1) a step of producing a compound (A) having a urea linkage, using an organic primary amine having at least one primary amino group per molecule and at least one compound selected from among carbon dioxide and carbonic acid derivatives, at a temperature lower than the thermal dissociation temperature of the urea linkage; and(2) a step of reacting the compound (A) with a carbonate ester to produce a carbamate.