170632-20-9Relevant academic research and scientific papers
1-Benzyl-3-(5′-hydroxymethyl-2′-furyl)-indazole (YC-1) derivatives as novel inhibitors against sodium nitroprusside-induced apoptosis
Lien, Jin-Cherng,Lee, Fang-Yu,Huang, Li-Jiau,Pan, Shiow-Lin,Guh, Jih-Hwa,Teng, Che-Ming,Kuo, Sheng-Chu
, p. 4947 - 4949 (2007/10/03)
Antiapoptotic agents based on 1-benzyl-3-(5′-hydroxymethyl-2′-furyl)indazole (22, YC-1) derivatives were explored for effective treatment of sepsis and septic shock. We found that compound 22, 1-benzyl-3-(5′-methoxymethyl-2′-furyl)indazole (27), and 1-phe
Synthesis of 1-benzyl-3-(5′-hydroxymethyl-2′-furyl)indazole analogues as novel antiplatelet agents
Le,Lien,Huang,Huang,Tsai,Teng,Wu,Cheng,Kuo
, p. 3746 - 3749 (2007/10/03)
1-Benzyl-3-(5′-hydroxymethyl-2′-furyl)indazole (28, YC-1) was selected as the lead compound for systemic structural modification. After screening for antiplatelet activity, SARs of YC-1 analogues were established. Among these potent active derivatives, co
