170640-17-2Relevant academic research and scientific papers
3'-Deoxy-3'-(vinylsulphonyl)thymidine - A New Reactive Analogue of AZT: Its Synthesis and Reactivities Towards Various Nucleophiles
Bera, Sanjib,Sakthivel, Kandasamy,Pathak, Tanmaya,Langley, Graham J.
, p. 7857 - 7866 (1995)
A reactive triatomic analogue of AZT, 3'-deoxy-3'-(vinylsulphonyl)thymidine has been synthesised from easily accessible starting material.The vinyl-sulphone nucleoside was reacted with a variety of nucleophiles to generate new classes of modified nucleosides where the functional groups were attached to the C-3' of a nucleoside through flexible ethyl sulphone spacer.
