17067-93-5Relevant academic research and scientific papers
Enantioselective synthesis of axially chiral multifunctionalized biaryls via asymmetric suzuki-miyaura coupling
Zhou, Yougui,Wang, Shouliang,Wu, Wenhao,Li, Qing,He, Yuwei,Zhuang, Yue,Li, Lanning,Pang, Jiyan,Zhou, Zhongyuan,Qiu, Liqin
, p. 5508 - 5511 (2013)
Substituted 2-formylarylboronic acids were successfully employed as substrates for asymmetric Suzuki-Miyaura coupling. By virtue of the coupling with dialkoxyphosphinyl substituted naphthyl bromides and 2-nitronaphthalen-1-yl triflouromethanesulfonate, a series of novel multifunctionalized axially chiral biaryls were prepared in 53-97% yields with up to 97% ee using palladium-Cy-MOP as the catalyst. The methodology provides a highly efficient and practical strategy for the synthesis of novel multifunctionalized axially chiral biaryls.
Oxidative Phoshonylation of Aromatics with Ammonium Cerium(IV) Nitrate
Kottmann, Hariolf,Skarzewski, Jacek,Effenberger, Franz
, p. 797 - 801 (2007/10/02)
Arylphosphonates 5 and 6 can be prepared in good yields in a one-step synthesis starting from arenes with tri- or diethylphosphites and cerium ammonium nitrate (CAN) as oxidant.The seletivity of the oxidative phosphonylation is relatively low; the reactive species is a phosphite radical cation.
