170707-15-0

Upstream product

• 889109-21-1 C₄₇H₆₂O₉ 
• 889109-12-0 tert-Butyl-[(2S,3R,4aS,8aS,9aR,10aR)-4a,5-dimethyl-2-((R)-2-methyl-3-phenylsulfanyl-propyl)-3,4,4a,7,8a,9,9a,10a-octahydro-2H-1,8,10-trioxa-anthracen-3-yloxy]-dimethyl-silane 
• 889109-11-9 (R)-3-[(2S,3R,4aS,8aS,9aR,10aR)-3-(tert-Butyl-dimethyl-silanyloxy)-4a,5-dimethyl-3,4,4a,7,8a,9,9a,10a-octahydro-2H-1,8,10-trioxa-anthracen-2-yl]-2-methyl-propan-1-ol 
• 858346-53-9 (2R,4aR,6R,7S,8aR,9aS,10aS)-6-(tert-Butyl-dimethyl-silanyloxy)-7-[(R)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propyl]-10a-methyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracene 
• 858346-21-1 (2R,3S,4aR,6S,7R,8aS)-7-Benzyloxy-6-(2-benzyloxy-ethyl)-2,6,8a-trimethyl-2-vinyl-octahydro-pyrano[3,2-b]pyran-3-ol 
• 858346-40-4 C₄₉H₆₈O₉ 
• 170707-10-5 C₄₈H₇₄O₉Si 
• 170707-06-9 C₄₉H₆₉O₁₄P 
• 170707-09-2 C₅₅H₈₈O₁₀Si₂ 
• 161984-82-3 C₅₂H₇₈O₁₀Si 
• 161984-91-4 C₄₇H₆₃BrO₁₁ 
• 170707-08-1 C₅₂H₈₄O₉Si₂ 
• 170707-07-0 C₄₉H₇₄O₁₀Si 
• 161984-87-8 C₅₁H₇₆O₉Si 

Downstream Products

• 170707-17-2 C₄₀H₅₈O₁₁S 

Relevant academic research and scientific papers

Improved synthesis of the A-G ring segment of brevetoxin B

An efficient synthesis of the A-G ring segment 2, a key intermediate for the total synthesis of brevetoxin B (1), was achieved in 37 steps and 5.0% overall yield. The intramolecular allylation of the O,S-acetal 22, prepared from the ABC ring segment 15 an

Total synthesis of brevetoxin B

The convergent total synthesis of brevetoxin B (1) has been achieved. The intramolecular allylation of the O,S-acetal 20, prepared from the α-chlorosulfide 17 and the alcohol 5, was carried out using AgOTf as a Lewis acid to give the diene 21, predominant

Total synthesis of brevetoxin B. 3. Final strategy and completion

The final strategy for the total synthesis of brevetoxin B (1) according to the retrosynthetic analysis shown in Scheme 1 is described. Starting with the tetracyclic ring system 8 [DEFG], the construction of the C ring was accomplished via an intramolecul