170707-48-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 170901-52-7 (2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hexane-1,3-diol 
• 170901-51-6 (E)-(2S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hex-3-enoic acid methyl ester 
• 134333-50-9 2,5-dimethoxy-3-nitrobenzaldehyde dimethyl acetal 

Downstream Products

• 170707-51-4 (2R,3S,5S,6R)-6-(2,5-Dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexane-1,2-diol 
• 206661-20-3 (2S,3E,5S,6R)-7-(2,5-dimethoxy-3-nitrophenyl)-4,7-dimethoxy-2,6-dimethyl-1-ene-3-heptanol 
• 206661-23-6 (2S,3R,4S,6S,7R)-7-(2,5-Dimethoxy-3-nitro-phenyl)-3,4,7-trimethoxy-2,6-dimethyl-heptan-1-ol 
• 206661-15-6 (2S,3R,4S,6S,7R)-7-(2,5-Dimethoxy-3-nitro-phenyl)-4,7-dimethoxy-2,6-dimethyl-1-trimethylsilanyloxy-heptan-3-ol 
• 206661-04-3 (3R,4S,6S,7R)-3-Benzyloxy-7-(2,5-dimethoxy-3-nitro-phenyl)-4,7-dimethoxy-6-methyl-heptan-2-ol 
• 206661-03-2 (2S,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexanal 
• 206661-08-7 (2R,3S,5S,6R)-2-(tert-Butyl-dimethyl-silanyloxy)-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexan-1-ol 
• 206661-16-7 [(2S,3R,4S,6S,7R)-7-(2,5-Dimethoxy-3-nitro-phenyl)-3,4,7-trimethoxy-2,6-dimethyl-heptyloxy]-trimethyl-silane 
• 206661-10-1 (3R,4S,6S,7R)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(2,5-dimethoxy-3-nitro-phenyl)-4,7-dimethoxy-6-methyl-heptan-2-ol 
• 206661-12-3 tert-Butyl-[(1R,2S,4S,5R)-5-(2,5-dimethoxy-3-nitro-phenyl)-1-isopropenyl-2,5-dimethoxy-4-methyl-pentyloxy]-dimethyl-silane 
• 206661-09-8 (2S,3S,5S,6R)-2-(tert-Butyl-dimethyl-silanyloxy)-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexanal 
• 206661-11-2 (3S,4S,6S,7R)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(2,5-dimethoxy-3-nitro-phenyl)-4,7-dimethoxy-6-methyl-heptan-2-one 
• 206661-07-6 1-[(1R,2S,4S,5R)-5,6-Bis-(tert-butyl-dimethyl-silanyloxy)-1,4-dimethoxy-2-methyl-hexyl]-2,5-dimethoxy-3-nitro-benzene 
• 206661-21-4 (2R,3R,4S,6S,7R)-7-(2,5-Dimethoxy-3-nitro-phenyl)-4,7-dimethoxy-2,6-dimethyl-heptane-1,3-diol 

Relevant academic research and scientific papers

Total Synthesis of Herbimycin A

(Equation presented) Herbimycin A (HA) belongs to a class of antibiotics known as the benzoquinoid ansamycins. Members of this class have shown promising biological activity as Hsp90 inhibitors. An enantioselective synthesis of HA is described, employing

Chiral crotylsilane-based approach to benzoquinoid ansamycins: Total synthesis of (+)-macbecin I

A highly convergent total synthesis of the antitumor antibiotic (+)- macbecin I (1) has been achieved through the homologation of the aldehyde 3 (C5-C21 aromatic fragment) to the E, Z-dienoate 2 by employing a sequential olefination strategy. Subsequent m