206661-03-2Relevant academic research and scientific papers
Chiral crotylsilane-based approach to benzoquinoid ansamycins: Total synthesis of (+)-macbecin I
Panek, James S.,Xu, Feng,Rondón, Ana C.
, p. 4113 - 4122 (2007/10/03)
A highly convergent total synthesis of the antitumor antibiotic (+)- macbecin I (1) has been achieved through the homologation of the aldehyde 3 (C5-C21 aromatic fragment) to the E, Z-dienoate 2 by employing a sequential olefination strategy. Subsequent m
