170707-64-9

Upstream product

• 206661-17-8 (2Z,6E)-(4S,5R,8S,9R,10S,12S,13R)-13-(2,5-Dimethoxy-3-nitro-phenyl)-9,10,13-trimethoxy-5-(4-methoxy-benzyloxy)-4,6,8,12-tetramethyl-trideca-2,6-dien-1-ol 
• 170707-61-6 (E)-(2R,3R,6S,7R,8S,10S,11R)-11-(2,5-Dimethoxy-3-nitro-phenyl)-7,8,11-trimethoxy-3-(4-methoxy-benzyloxy)-2,4,6,10-tetramethyl-undec-4-enal 
• 170707-62-7 (2Z,6E)-(4S,5R,8S,9R,10S,12S,13R)-13-(2,5-Dimethoxy-3-nitro-phenyl)-9,10,13-trimethoxy-5-(4-methoxy-benzyloxy)-4,6,8,12-tetramethyl-trideca-2,6-dienoic acid methyl ester 
• 170707-60-5 2,5-Dimethoxy-1-nitro-3-[(7E,11E)-(1R,2S,4S,5R,6S,9R,10S)-1,4,5,14-tetramethoxy-9-(4-methoxy-benzyloxy)-2,6,8,10-tetramethyl-tetradeca-7,11-dienyl]-benzene 
• 170707-59-2 4-[(E)-(1R,4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-1-((E)-(S)-5-methoxy-1-methyl-pent-2-enyl)-2,4,8-trimethyl-non-2-enyloxymethyl]-phenol 
• 134333-50-9 2,5-dimethoxy-3-nitrobenzaldehyde dimethyl acetal 
• 170707-52-5 (2S,4S,5R)-5-(2,5-dimethoxy-3-nitrophenyl)-2,5-dimethoxy-4-methylpentanal 
• 170707-51-4 (2R,3S,5S,6R)-6-(2,5-Dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexane-1,2-diol 
• 170707-54-7 (2R,3R,4S,6S,7R)-7-(2,5-dimethoxy-3-nitrophenyl)-3,4,7-trimethoxy-2,6-dimethylheptanal 
• 170901-52-7 (2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hexane-1,3-diol 
• 170707-56-9 (E)-(4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-2,4,8-trimethyl-non-2-en-1-ol 
• 170707-57-0 (E)-(4S,5R,6S,8S,9R)-9-(2,5-Dimethoxy-3-nitro-phenyl)-5,6,9-trimethoxy-2,4,8-trimethyl-non-2-enal 
• 170707-50-3 (2R,3S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-3,6-dimethoxy-5-methyl-hexan-1-ol 
• 170901-51-6 (E)-(2S,5S,6R)-2-Benzyloxy-6-(2,5-dimethoxy-3-nitro-phenyl)-6-methoxy-5-methyl-hex-3-enoic acid methyl ester 

Downstream Products

• 130740-44-2 macbecin I 
• 206661-19-0 (4E,6Z,10E)-(8S,9R,12S,13R,14S,16S,17R)-13,14,17,20,22-Pentamethoxy-9-(4-methoxy-benzyloxy)-4,8,10,12,16-pentamethyl-2-aza-bicyclo[16.3.1]docosa-1⁽²²⁾,4,6,10,18,20-hexaen-3-one 
• 170707-67-2 (2E,4Z,8E)-(6S,7R,10S,11R,12S,14S,15R)-15-(3-Amino-2,5-dimethoxy-phenyl)-11,12,15-trimethoxy-7-(4-methoxy-benzyloxy)-2,6,8,10,14-pentamethyl-pentadeca-2,4,8-trienoic acid 
• 170707-66-1 (2E,4Z,8E)-(6S,7R,10S,11R,12S,14S,15R)-15-(3-Amino-2,5-dimethoxy-phenyl)-11,12,15-trimethoxy-7-(4-methoxy-benzyloxy)-2,6,8,10,14-pentamethyl-pentadeca-2,4,8-trienoic acid ethyl ester 
• 170707-65-0 (2E,4Z,8E)-(6S,7R,10S,11R,12S,14S,15R)-15-(2,5-Dimethoxy-3-nitro-phenyl)-11,12,15-trimethoxy-7-(4-methoxy-benzyloxy)-2,6,8,10,14-pentamethyl-pentadeca-2,4,8-trienoic acid ethyl ester 

Relevant academic research and scientific papers

Chiral crotylsilane-based approach to benzoquinoid ansamycins: Total synthesis of (+)-macbecin I

A highly convergent total synthesis of the antitumor antibiotic (+)- macbecin I (1) has been achieved through the homologation of the aldehyde 3 (C5-C21 aromatic fragment) to the E, Z-dienoate 2 by employing a sequential olefination strategy. Subsequent m