170710-56-2

Upstream product

• 583-60-8 2-Methylcyclohexanone 
• 1193-47-1 2,2-dimethyl-cyclohexanone 
• 57188-99-5 3-butyn-2-yl tetrahydropyranyl ether 
• 79893-64-4 2-ethyl-6,6-dimethyl-1-cyclohexanone 

Downstream Products

• 132719-15-4 (+/-)-3-(2'-ethyl-1'-hydroxy-6',6'-dimethylcyclohexyl)-1-methyl-2-propynyl acetate 
• 132719-16-5 (+/-)-3-(2'-ethyl-6',6'-dimethyl-1'-cyclohexene-1'-yl)-1-methyl-2-propynyl acetate 
• 132719-14-3 (+/-)-(E)-4-(2'-ethyl-6',6'-dimethyl-1'-cyclohexene-1'-yl)-3-buten-2-one 
• 132719-17-6 (+/-)-(E)-4-(2'-ethyl-6',6'-dimethyl-1'-cyclohexene-1'-yl)-3-buten-2-ol 
• 79893-65-5 (+/-)-4-(2'-ethyl-1'-hydroxy-6',6'-dimethylcyclohexyl)-but-3-yn-2-ol 

Relevant academic research and scientific papers

Synthesis and Biological Activity of 7'-, 8'-, and 9'-Alkyl Analogues of Abscisic Acid

In order to examine the hypothesis of pseudo-symmetry in the abscisic acid (ABA) molecule, (+/-)-7'-,8'-, and 9'-methyl, and (+/-)-7'-, 8'-, and 9'-ethyl analogues of abscisic acid, whose pseudo-symmetry is decreased, weresynthesized and, after optical resolution, tested for their inhibitory activity in four bioassays.The correlation of the decrease in the activity of (-)-7'- and 9'-alkyl-ABAs with that of (+)-9'- and 7'-alkyl-ABAs, respectively, seemed to agree with the hypothesis.The decrease in activity by alkylating C-8' of (+)-ABA was smaller than that by alkylating C-7' and C-9' of (+)-ABA, indicating that the activity was relatively unaffected by the bulky group at C-8' of (+)-ABA.Alkylation of C-8' and C-9', especially that of C-8', of (-)-ABA markedly reduced the activity.If the high activity of unnatural (-)-ABA is attributable to the pseudo-symmetry of the molecule, C-8' of (-)-ABA would occupy the space facing the re-face of C-2' in natural (+)-ABA.The low activity of (-)-8'-alkyl-ABA suggests the presence of a strict steric requirement of the binding sites to occupy the re-face of C-2' in (+)-ABA.