170710-98-2

Upstream product

• 123190-15-8 2-((S)-2-Hydroxy-1-phenyl-ethyl)-6,7-dimethoxy-3,4-dihydro-isoquinolinium; bromide 
• 123190-11-4 1-bromoisochroman 
• 123190-12-5 2-(2-bromoethyl)-4,5-(dimethoxy)benzaldehyde 
• 170711-01-0 (3S,10bR)-8,9-Dimethoxy-10b-methyl-3-phenyl-2,3,6,10b-tetrahydro-oxazolo[2,3-a]isoquinolin-5-one 
• 20989-17-7 (2S)-2-phenylglycinol 
• 170710-97-1 (S)-2-((S)-2-Hydroxy-1-phenyl-ethyl)-6,7-dimethoxy-1-methyl-1,4-dihydro-2H-isoquinolin-3-one 
• 917-64-6 methyl magnesium iodide 
• 123284-47-9 (3S,10bR)-8,9-dimethoxy-3-phenyl-2,3,5,6-tetrahydro-10bH-oxazolo<2.3-a>isoquinoline 

Relevant academic research and scientific papers

SYNTHESES OF CHIRAL OXAZOLOTETRAHYDROISOQUINOLINE AND ITS ASYMMETRIC ALKYLATION. SYNTHESIS OF (S)-(-)- AND (R)-(+)-SALSOLIDINES

The isoquinolinium bromide (4), on treatment with base, underwent cyclization to give the chiral oxazolotetrahydroisoquinoline (5) with a high diastereoselectivity, which was converted to optically pure salsolidine.