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170729-76-7

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170729-76-7 Usage

Uses

Different sources of media describe the Uses of 170729-76-7 differently. You can refer to the following data:
1. NK-1 receptor antagonists for treating severe anxiety disorders. Antidepressant
2. Defluoro Aprepitant (Aprepitant EP Impurity A) is a NK-1 receptor antagonists for treating severe anxiety disorders. Antidepressant.

Check Digit Verification of cas no

The CAS Registry Mumber 170729-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,7,2 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 170729-76:
(8*1)+(7*7)+(6*0)+(5*7)+(4*2)+(3*9)+(2*7)+(1*6)=147
147 % 10 = 7
So 170729-76-7 is a valid CAS Registry Number.

170729-76-7 Well-known Company Product Price

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  • (1041992)  Desfluoro Aprepitant  United States Pharmacopeia (USP) Reference Standard

  • 170729-76-7

  • 1041992-15MG

  • 14,500.98CNY

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170729-76-7Downstream Products

170729-76-7Relevant articles and documents

Structural optimization affording 2-(R)-(1-(R)-3,5- bis(trifluoromethyl)phenylethoxy)-3'-(S)-(4-fluoro)phenyl-4-(3-oxo-1,2,4- triazol-5-yl)methylmorpholine, a potent, orally active, long-acting morpholine acetal human NK-1 receptor antagonist

Hale, Jeffrey J.,Mills, Sander G.,MacCoss, Malcolm,Finke, Paul E.,Cascieri, Margaret A.,Sadowski, Sharon,Ber, Elzbieta,Chicchi, Gary G.,Kurtz, Marc,Metzger, Joseph,Eiermann, George,Tsou, Nancy N.,Tattersall, F. David,Rupniak, Nadia M. J.,Williams, Angela R.,Rycroft, Wayne,Hargreaves, Richard,MacIntyre, D. Euan

, p. 4607 - 4614 (2007/10/03)

Structural modifications requiring novel synthetic chemistry were made to the morpholine acetal human neurokinin-1 (hNK-1) receptor antagonist 4, and this resulted in the discovery of 2-(R)-(1-(R)-3,5- bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phe

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