159706-35-1

Basic information

• Product Name: 2-Morpholinone, 3-phenyl-4-(phenylmethyl)-, (3S)-
• CAS NO: 159706-35-1
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.327
• Mol File: 159706-35-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Morpholinone, 3-phenyl-4-(phenylmethyl)-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Morpholinone, 3-phenyl-4-(phenylmethyl)-, (3S)-(159706-35-1)
• EPA Substance Registry System: 2-Morpholinone, 3-phenyl-4-(phenylmethyl)-, (3S)-(159706-35-1)

Safety Data

• Hazardous Substances Data: 159706-35-1(Hazardous Substances Data)

Upstream product

• 1319189-53-1 C₁₈H₂₃BrO₆ 
• 104-63-2 N-Benzylethanolamine 
• 1417715-05-9 O,O'-di(α-bromo-α-phenylacetyl)-N,N,N',N'-tetramethyl-L-tartaric diamide 
• 1417715-03-7 O,O'-di(α-bromo-α-phenylacetyl)-L-tartaric acid diisopropyl ester 
• 2935-35-5 (S)-2-phenylglycine 
• 100-39-0 benzyl bromide 
• 106-93-4 ethylene dibromide 
• 1192307-86-0 (2-methoxy-2-oxo-(S)-1-phenylethyl) α-bromophenylacetate 
• 40297-86-7 benzylamino-phenyl-acetic acid 

Downstream Products

• 159706-37-3 (2R,3S)-4-Benzyl-2-(3,5-bis-trifluoromethyl-benzyloxy)-3-phenyl-morpholine 
• 159706-36-2 4-Benzyl-2-(S)-(3,5-bis(trifluoromethyl)benz-yloxy)-3-(S)-phenylmorpholine 
• 170729-72-3 2-(R)-(3,5-bis(tri-fluoro-methyl)benzoyloxy)-3-(S)-phenyl-4-benzyl morpholine 
• 159813-00-0 (2S,3S)-2-((3,5-bis(trifluoromethyl)benzyl)oxy)-3-phenylmorpholine 
• 170729-76-7 aprepitant 
• 170729-76-7 5-{(2R,3S)-2-[(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-phenyl-morpholin-4-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one 
• 171338-33-3 [2R-[2α(R*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine 
• 170729-74-5 2-(R)-(1-(S)-(3,5-bis(tri-fluoromethyl)phenyl)ethoxy)-3-(S)-phenyl morpholine 
• 170729-73-4 2-(R)-(1-(3,5-bis(tri-fluoromethyl)phenyl)ethenyloxy)-3-(S)-phenyl-4-benzyl morpholine 
• 171243-05-3 (2R,3S)-4-Benzyl-2-[1-(3-fluoro-5-trifluoromethyl-phenyl)-vinyloxy]-3-phenyl-morpholine 
• 171243-09-7 (2R,3S)-4-Benzyl-3-phenyl-2-[1-(3-trifluoromethyl-phenyl)-vinyloxy]-morpholine 
• 170729-83-6 (2R,3S)-2-[(R)-1-(3-Fluoro-5-trifluoromethyl-phenyl)-ethoxy]-3-phenyl-morpholine 

Relevant articles and documents

L-tartaric acid as a new chiral auxiliary for asymmetric synthesis of piperazinones, morpholinones, dihydroquinoxalinones and dihydrobenzoxazinones

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Simple and efficient one pot synthetic protocol to construct morpholin-2-ones

A new one pot synthetic method to construct 3-substituted morpholine-2-one derivatives is presented. Amino acids refluxed with 1,2-dibromoethane and potassium carbonate in acetonitrile followed by treatment with benzyl bromide in same pot furnished the 3-

An asymmetric synthesis of 3-aryl-1,4-oxazin-2-ones: Synthesis of a key intermediate of an NK1 receptor antagonist

Pyrrolidine derived (S)-lactamide auxiliaries mediate a highly diastereoselective coupling reaction between racemic α-halo acids and N-benzylethanolamine. The adducts are readily cyclized upon treatment with a catalytic amount of TsOH giving the above tit