170789-65-8

Basic information

• Product Name: Propanedioic acid, [[4-(bromomethyl)phenyl]methylene]-, diethyl ester
• CAS NO: 170789-65-8
• Molecular Formula: C15H17BrO4
• Molecular Weight: 341.202
• Mol File: 170789-65-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [[4-(bromomethyl)phenyl]methylene]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [[4-(bromomethyl)phenyl]methylene]-, diethyl ester(170789-65-8)
• EPA Substance Registry System: Propanedioic acid, [[4-(bromomethyl)phenyl]methylene]-, diethyl ester(170789-65-8)

Safety Data

• Hazardous Substances Data: 170789-65-8(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 104-87-0 4-methyl-benzaldehyde 
• 14111-33-2 diethyl 2-(4-methylbenzylidene)malonate 

Downstream Products

• 170790-93-9 2-(Bromo-difluoro-methyl)-2-{[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-phenyl-methyl}-malonic acid diethyl ester 
• 170790-52-0 5,7-Dimethyl-3-[[4-[2,2-bis(ethoxycarbonyl)-2-methyl-1-phenylethyl]phenyl]methyl]-2-ethyl-3H-imidazo[4,5-b]pyridine 
• 170790-40-6 5,7-Dimethyl-3-[[4-[2,2-bis(ethoxycarbonyl)-1-phenylethyl]phenyl]methyl]-2-ethyl-3H-imidazo[4,5-b]pyridine 

Relevant articles and documents

IMIDAZOPYRIDINE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS

The present invention relates to new imidazopyridine derivatives of formula I STR1 wherein: one of A, B, C and D is N and the other are CR, wherein each R independently represents hydrogen, C 1-4 alkyl, COOH or halogen; R 1 represents C 1-4 alkyl or C 3-7 cycloalkyl; Ar 1 represents phenyl or pyridyl which can be optionally substituted; V represents C 1-4 alkyl, C 3-7 cycloalkyl, aryl, aryl-(C 1-4)alkyl or a 5-or 6-membered aromatic heterocycle; the group X-Y represents C=C or CH--CR 3 ; R 3 represents hydrogen, C 1-4 alkyl or aryl-(C 1-4)alkyl; Z represents among others--CO 2 R 4,--tetrazol-5-yl,--CONHSO 2 R 4,--CONR 4 R 5,--CH 2 NHSO 2 R 4 ; R 4 and R 5 independently represent hydrogen, C 1-4 alkyl, aryl, aryl-(C 1-4) alkyl or perfluoro-(C 1-4) alkyl; W represents hydrogen, cyano, C 1-4 alkyl, C 1-4 haloalkyl, C 3-7 cycloalkyl, aryl, aryl-(C 1-4)alkyl, C 1-4 alkylsulfonyl, C 1-4 alkylsulfinyl, C 1-4 alkylthio, C 1-4 alkoxy, C 1-4 alkylcarbonyl, halogen, hydroxymethyl or C 1-4 alkoxymethyl, or W can have any of the meanings disclosed for Z. These compounds are angiotensin II antagonists.

New imidazopyridine derivatives as angiotensin II antagonists.

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