17086-76-9

Basic information

• Product Name: Cyasterone
• Synonyms: CYASTERONE;(3S,4S,5R)-4-[(2R,3R)-2,3-Dihydroxy-3-[(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-6-oxo-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]butyl]-3,5-dimethyloxolan-2-one;(22R,24S,25S,28R)-2β,3β,14,20,22,28-Hexahydroxy-6-oxo(26-13C)-5β-stigmasta-7-ene-26-oic acid γ-lactone;(22r,24s,25s,28r)-gamma-lacton;2-beta,3-beta,14,20,22,28-hexahydroxy-6-oxo-5-beta-stigmast-7-en-26-oicaci;cyasteron;7,(5BETA)-CHOLESTEN-26-CARBOXYLIC ACID-24BETA-(1-HYDROXYETHYL)-2BETA, 3BETA, 14ALPHA,20BETA, 22R-PENTOL-6-ONE GAMMA-LACTONE;Cyasterone, 98%, from Cyathula officinalis K.C. Kuan
• CAS NO: 17086-76-9
• Molecular Formula: C₂₉H₄₄O₈
• Molecular Weight: 520.65
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 17086-76-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 164～166℃
• Boiling Point: 735.2 °C at 760 mmHg
• Flash Point: 239.2 °C
• Appearance: /
• Density: 1.31 g/cm³
• Vapor Pressure: 6E-25mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 14.12±0.70(Predicted)
• CAS DataBase Reference: Cyasterone(CAS DataBase Reference)
• NIST Chemistry Reference: Cyasterone(17086-76-9)
• EPA Substance Registry System: Cyasterone(17086-76-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 17086-76-9(Hazardous Substances Data)

Usage

Uses

Cyasterone is a phytoecdysteroid that has been shown to prevent the hepatotoxic action of CCl4 when administered to rats with hepatitis.

InChI:InChI=1/C29H44O8/c1-14-16(15(2)37-25(14)34)10-24(33)28(5,35)23-7-9-29(36)18-11-20(30)19-12-21(31)22(32)13-26(19,3)17(18)6-8-27(23,29)4/h11,14-17,19,21-24,31-33,35-36H,6-10,12-13H2,1-5H3/t14-,15+,16-,17-,19-,21+,22-,23-,24+,26+,27+,28+,29+/m0/s1

Downstream Products

• 10162-99-9 (2S,3R,5R,10R,13R,14S)-17-Acetyl-2,3,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one 
• 103768-04-3 (2S,3R,5R,10R,13R,14S)-17-{(1R,2R)-1,2-Dihydroxy-6-[3-(4-hydroxy-phenyl)-propoxy]-1,5-dimethyl-hexyl}-2,3,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one 

Related news

Original articleAnti-proliferation effects, efficacy of Cyasterone (cas 17086-76-9) in vitro and in vivo and its mechanism08/11/2019

Cyasterone was demonstrated potential inhibition effect in mouse skin carcinoma cells in published report. However, the molecular mechanisms of the cyasterone on cells remain unknown. Herein, we investigated the effects of cyasterone-induced apoptosis in A549 and MGC823 cells in vitro. MTT assay...detailed