170860-65-8Relevant academic research and scientific papers
Optionally substituted phenylimidazolidines, their preparation process and intermediates, their use as medicaments and the pharmaceutical compositions containing them
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, (2008/06/13)
A compound in all possible racemic, enantiomeric and diastereoisomer forms of the formula STR1 wherein Y is --O--, Z 2 is --CF 3, Z 1 is --CN or --NO 2, X is --O-- or --S--, R 3 is hydrogen or alkyl of 1 to 4 carbon atoms optionally substituted by at least one halogen or --CN and R 4 and R 5 are individually alkyl of 1 to 4 carbon atoms optionally substituted with a member of the group consisting of halogen, --OH, esterified or etherified or protected hydroxy and phenylthio optionally substituted by halogen or --OH, and wherein at least one of R 4 and R 5 is substituted having antiandrogenic activity.
