170897-60-6

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 101331-92-4 4-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-L-threose 
• 136032-73-0 4-O-(tert-butyldiphenylsilyl)-2,3-O-isopropylidene-L-threitol 
• 50622-09-8 2,3-O-isopropylidene-L-threitol 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 1309688-70-7 C₃₀H₄₂O₅Si 
• 147368-76-1 (4S,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-vinyl-[1,3]dioxolan-2-one 

Relevant academic research and scientific papers

Efficient synthesis of the C1-C9 fragment of 7,8-O-isopropylidene protected iriomoteolide 3a derivative

An efficient and stereoselective synthesis of the C1-C9 moiety of the 7,8-O-isopropylidene protected iriomoteolide 3a derivative has been accomplished. In our strategy, we employed olefin cross-metathesis of the L-(+)-tartaric acid derivative (((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl) methoxy)(tert-butyl) diphenylsilane with a synthesized methyl (S)-3-methylhex-5-enate to successfully provide the correct olefin geometry of the desired fragment.

Highly regio-, (E)-stereo-, and diastereoselective SN2′ addition of organocuprates to chiral allylic cyclic carbonates

Reaction of the cyclic carbonates of acyclic vinyl diols with RCu(CN)Li· BF3, RCu(CN)MgBr·BF3, or RMgBr·CuI (cat) in THF at -78°C proceeded in SN2′ fashion and resulted in the formation of alkylated (E)-allylic alcohols wi