1709-03-1

Basic information

• Product Name: 2-CHLORO-N-(3-METHOXY-PROPYL)-ACETAMIDE
• Synonyms: 2-CHLORO-N-(3-METHOXY-PROPYL)-ACETAMIDE;acetamide, 2-chloro-N-(3-methoxypropyl)-;2-chloro-N-(3-methoxypropyl)ethanamide
• CAS NO: 1709-03-1
• Molecular Formula: C6H12ClNO2
• Molecular Weight: 165.61798
• Mol File: 1709-03-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 30°C
• Boiling Point: 88 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.1838 (rough estimate)
• Refractive Index: 1.4712 (estimate)
• PKA: 14.03±0.46(Predicted)
• CAS DataBase Reference: 2-CHLORO-N-(3-METHOXY-PROPYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(3-METHOXY-PROPYL)-ACETAMIDE(1709-03-1)
• EPA Substance Registry System: 2-CHLORO-N-(3-METHOXY-PROPYL)-ACETAMIDE(1709-03-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1709-03-1(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 5332-73-0 3-methoxypropylamine 

Relevant articles and documents

Copper(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from o-halophenols and 2-chloroacetamides

We developed an efficient and convenient method for preparing N-substituted 2H-1,4-benzoxazin-3-(4H)-ones from 2-halophenols via a nueleophilic substitution with 2-chlo-roacetamides followed by a Cul-catalyzed coupling cyclization. A broad spectrum of substrates can be effectively employed to afford the desired products in good yields. Since this method involves simple reaction conditions, a short reaction time, and a broad substrate scope, it is particularly attractive for the efficient preparation of biologically and medicinally interesting molecules.