17090-71-0

Basic information

• Product Name: 2-(2-furyl)-2-oxo-acetaldehyde
• Synonyms: 2-(2-furyl)-2-oxo-acetaldehyde;2-(FURAN-2-YL)-2-OXOACETALDEHYDE;2-Furylglyoxal
• CAS NO: 17090-71-0
• Molecular Formula: C₆H₄O₃
• Molecular Weight: 124.1
• Mol File: 17090-71-0.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 168.7°C at 760 mmHg
• Flash Point: 64.6°C
• Appearance: /
• Density: 1.227g/cm³
• Vapor Pressure: 1.6mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: 2-(2-furyl)-2-oxo-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-furyl)-2-oxo-acetaldehyde(17090-71-0)
• EPA Substance Registry System: 2-(2-furyl)-2-oxo-acetaldehyde(17090-71-0)

Safety Data

• Hazardous Substances Data: 17090-71-0(Hazardous Substances Data)

Usage

General Description

2-(2-furyl)-2-oxo-acetaldehyde is a chemical compound with the molecular formula C7H6O3. It is a member of the aldehyde family, containing a furan ring and a carbonyl group. 2-(2-furyl)-2-oxo-acetaldehyde is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities. It can be prepared by the oxidation of 2-furfuryl alcohol or the hydrolysis of 2-(2-furyl)-2-hydroxyacetaldehyde. 2-(2-furyl)-2-oxo-acetaldehyde has been studied for its potential use as a flavoring agent in food products and also for its antibacterial and antitumor properties. Its unique structure and reactivity make it a versatile building block for the synthesis of various organic compounds.

InChI:InChI=1/C6H4O3/c7-4-5(8)6-2-1-3-9-6/h1-4H

Upstream product

• 55984-18-4 1-(furan-2-yl)-2-iodoethanone 
• 1192-62-7 1-(2-furyl)-1-ethanone 

Downstream Products

• 91037-91-1 2-(2-furoyl)-5-(2-furyl)-1H-imidazole 
• 91037-91-1 2-(2-furoyl)-4-(2-furyl)-1H-imidazole 
• 120347-25-3 2-(2-furoyl)-4-(2-furyl)-1-propylimidazole 
• 99021-00-8 (1,3-diphenyl-imidazolidin-2-yl)-furan-2-yl-methanone 
• 60963-71-5 1-tert-butylamino-3-[4-(4-furan-2-yl-1⁽³⁾H-imidazol-2-yl)-phenoxy]-propan-2-ol 
• 77726-46-6 (2E)-2,2'-(1-(furan-2-yl)ethane-1,2-diylidene)bis(1-phenylhydrazine) 
• 17576-50-0 furan-2-yl-oxo-acetaldehyde phenylhydrazone 
• 494-21-3 2-furan-2-yl-quinoxaline 
• 39685-31-9 7-[(Z)-2-Furyl-2-methoxyiminoacetamido]-3-acetoxymethyl-3-cephalosporanic acid 
• 2976-01-4 1-(furan-2-yl)-3-phenylpropan-1-one 

Relevant articles and documents

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Catalytic Asymmetric Darzens-Type Epoxidation of Diazoesters: Highly Enantioselective Synthesis of Trisubstituted Epoxides

Highly enantioselective Darzens-type epoxidation of diazoesters with glyoxal derivatives was accomplished using a chiral boron–Lewis acid catalyst, which facilitated asymmetric synthesis of trisubstituted α,β-epoxy esters. In the presence of a chiral oxazaborolidinium ion catalyst, the reaction proceeded in high yield (up to 99 %) with excellent enantio- and diastereoselectivity (up to >99 % ee and >20:1 dr, respectively). The synthetic potential of this method was illustrated by conversion of the products to various compounds such as epoxy γ-butyrolactone, tertiary β-hydroxy ketone and epoxy diester.

Visible-Light-Induced Regioselective Dicarbonylation of Indolizines with Oxoaldehydes via Direct C-H Functionalization

A metal-free system for regioselective dehydrogenative cross-couplings between indolizines and oxoaldehydes catalyzed by visible light under mild conditions has been described. As an atom economical and eco-friendly protocol, the reaction proceeds in good yields using inexpensive, readily available visible-light sources and the environmentally friendly oxidant oxygen. Various valuable 1,2-dicarbonyl derivatives attached to an indolizine core were easily accessed by the direct dicarbonylation of the sp2 C-H bond.