494-21-3 Usage
Structure
Quinoxaline ring fused with a furan ring
The compound is formed by the fusion of a quinoxaline ring (a bicyclic aromatic compound containing nitrogen atoms) and a furan ring (a five-membered aromatic ring with one oxygen atom).
Type of compound
Heterocyclic compound
2-(furan-2-yl)quinoxaline is classified as a heterocyclic compound because it contains one or more atoms other than carbon (such as nitrogen and oxygen) in its aromatic ring structure.
Potential applications
Pharmaceutical and material science industries
The compound has potential uses in the pharmaceutical industry due to its biological activities, and in the material science industry due to its unique electronic and optical properties.
Biological activities
Antitumor agent, antifungal agent, and fluorescent probe for detecting metal ions
2-(furan-2-yl)quinoxaline has been studied for its role in inhibiting the growth of cancer cells, fighting fungal infections, and as a probe for detecting the presence of metal ions through fluorescence.
Electronic and optical properties
Potential use in organic light-emitting diodes (OLEDs) and optoelectronic devices
The compound's unique electronic and optical properties make it a promising candidate for use in OLEDs and other optoelectronic devices, which can be used in various applications such as displays, lighting, and sensors.
Ongoing research and development
Wide range of applications
2-(furan-2-yl)quinoxaline continues to be the subject of research and development due to its potential applications in various fields, including pharmaceuticals, material science, and optoelectronics.
Check Digit Verification of cas no
The CAS Registry Mumber 494-21-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 494-21:
(5*4)+(4*9)+(3*4)+(2*2)+(1*1)=73
73 % 10 = 3
So 494-21-3 is a valid CAS Registry Number.
494-21-3Relevant articles and documents
A One-pot Synthesis of Cyclic Pyrido[1,2-a]quinoxaline Phosphate, a New Molecule of Biological Importance from a Quinoxaline Derivative of Sugar
Goswami, Shyamaprosad,Adak, Avijit Kumar
, p. 678 - 679 (2003)
A five membered cyclic pyrido[1,2-a]quinoxaline phosphate has been first synthesized in one step in a good yield by phosphorylation of the quinoxaline derivative of sugar 1a with (PhO)P(O)Cl2. Phosphorylation of the tetrols (1a and 1b) and the diol acetals with other phosphorylating agents, however, affords a dehydration product 2-(2-furyl)quinoxaline.
Iridium-Catalyzed Carbenoid Insertion of Sulfoxonium Ylides for Synthesis of Quinoxalines and β-Keto Thioethers in Water
Xu, Yingying,Huang, Xin,Lv, Guanghui,Lai, Ruizhi,Lv, Songyang,Li, Jianglian,Hai, Li,Wu, Yong
, p. 4635 - 4638 (2020/07/04)
Sulfoxonium ylides as safe carbene precursors are described for iridium-catalyzed carbene insertions and annulation, providing a facile and green approach to access a variety of quinoxaline derivatives in water. This water-mediated method also allows the preparation of β-keto thioethers under mild condition.
One-step approach for the synthesis of functionalized quinoxalines mediated by T3P-DMSO or T3P: Via a tandem oxidation-condensation or condensation reaction
Harsha, Kachigere B.,Rangappa, Kanchugarkoppal S.
, p. 57154 - 57162 (2016/07/07)
An easy and efficient propylphosphonic anhydride (T3P)-DMSO or T3P mediated oxidation-condensation or condensation reaction for the synthesis of quinoxalines derived from the interaction of different arrays of condensing partners with ortho-phenylene diamines (o-PDs) under simple and mild reaction conditions in one step has been reported for the first time.
