170959-58-7

Upstream product

• 17012-49-6 5,7-dibromo-8-methoxyquinoline 
• 98-80-6 phenylboronic acid 

Downstream Products

• 172795-91-4 2,2-dimethyl-N-(2-(8-methoxy-5-phenyl-7-quinolyl)phenyl)propanamide 
• 173729-04-9 3,7-dibromo-8-methoxy-5-phenylquinoline 
• 172795-94-7 7-(2-azidophenyl)-8-methoxy-5-phenylquinoline 
• 172795-92-5 7-(2-aminophenyl)-5-phenyl-8-methoxyquinoline 

Relevant academic research and scientific papers

NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY

A compound of the formula (I): wherein Z4, Z5 and Z9 each is independently carbon atom or nitrogen atom; Y is hydroxy, mercapto or amino; RA is a group of the formula: (wherein C ring is nitrogen-containing heteroaryl) has an inhibitory activity against integrase.

Synthesis of 11H-pyrido[2,3-a]carbazoles and 6H-pyrido[3,2-b]carbazoles from 8-methoxy bromoquinolines

Cross-coupling reaction via substituted 7-bromoquinolines 1, 8 and (2-aminophenyl)boric acids afforded substituted 7-(2-aminophenyl)quinolines 3a-b, 10 from which synthesis of either 11H-pyrido[2,3-a]carbazoles 4a-b, 11 via C-8 cyclization or 6H-pyrido[3,

Synthesis of 7H-pyrido[2,3-c]carbazoles from 5-bromo-8-methoxyquinolines via coupling and azide cyclization reactions

A new strategy for the synthesis of substituted 7H-pyrido[2,3-c]carbazoles has been developed from substituted 5-bromoquinolines by using cross-coupling reaction with (2-aminophenyl)boric acids, followed by a regioselective azide cyclization.