170997-04-3

Upstream product

• 172540-28-2 ((5S)-2,2-bis-(trifluoromethyl)-4-oxo-1,3-dioxolan-5-yl)-acetyl chloride 
• 172540-27-1 [(5S)-2,2-Bis(trifluoromethyl)-4-oxo-1,3-dioxolan-5-yl] acetic acid 
• 172540-29-3 <(5S)-2,2-Bis(trifluoromethyl)-4-oxo-1,3-dioxolan-5-yl>methyl isocyanate 
• 100-51-6 benzyl alcohol 

Relevant academic research and scientific papers

New Efficient Strategy for the Incorporation of (S)-Isoserine into Peptides

A new efficient synthesis of (S)-isoserine derivatives from (S)-malic acid using hexafluoroacetone as protecting and activating reagent is described.Via this route (S)-isoserine is obtained as mono- and diactivated species suitable for the incorporation of isoserine into the N- and C-terminal positions of peptides.