Journal of Organic Chemistry p. 7641 - 7645 (1995)
Update date:2022-08-05
Topics:
Burger, Klaus
Windeisen, Elisabeth
Pires, Raul
A new efficient synthesis of (S)-isoserine derivatives from (S)-malic acid using hexafluoroacetone as protecting and activating reagent is described.Via this route (S)-isoserine is obtained as mono- and diactivated species suitable for the incorporation of isoserine into the N- and C-terminal positions of peptides.
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