17100-64-0

Basic information

• Product Name: 2-BROMO-5-HYDROXYMETHYL-ANISOLE
• Synonyms: 2-BROMO-5-HYDROXYMETHYL-ANISOLE;(4-broMo-3-Methoxyphenyl)Methanol;4-Bromo-3-methoxybenzyl alcohol;Benzyl alcohol, 4-bromo-3-methoxy-
• CAS NO: 17100-64-0
• Molecular Formula: C₈H₉BrO₂
• Molecular Weight: 217.07
• Mol File: 17100-64-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 306.8 °C at 760 mmHg
• Flash Point: 139.3 °C
• Appearance: /
• Density: 1.513 g/cm³
• Refractive Index: 1.57
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.04±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-5-HYDROXYMETHYL-ANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-HYDROXYMETHYL-ANISOLE(17100-64-0)
• EPA Substance Registry System: 2-BROMO-5-HYDROXYMETHYL-ANISOLE(17100-64-0)

Safety Data

• Hazardous Substances Data: 17100-64-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-hydroxymethyl-anisole, also known as 5-bromo-2-methoxy-phenylmethanol, is a chemical compound used in the synthesis of pharmaceuticals and organic compounds. It is a derivative of anisole, a colorless liquid with a characteristic aromatic odor, and is widely used as a flavoring agent in food and beverages. The compound is primarily used as an intermediate in the production of various pharmaceuticals and agrochemicals, as well as in the manufacturing of fragrance and flavoring compounds. It is also used as a raw material in the production of antioxidants and ultraviolet absorbers. The compound is available in solid form and is considered to be stable under normal conditions, with no known hazardous effects on human health or the environment.

InChI:InChI=1/C8H9BrO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-4,10H,5H2,1H3

Upstream product

• 6971-51-3 3-methoxybenzyl alcohol 
• 99-06-9 3-Carboxyphenol 
• 14348-38-0 4-bromo-3-hydroxybenzoic acid 
• 77-78-1 dimethyl sulfate 
• 17100-63-9 methyl 4-bromo-3-methoxybenzoate 
• 56256-14-5 4-bromo-3-methoxy-benzoic acid 

Downstream Products

• 113081-49-5 1-bromo-4-(chloromethyl)-2-methoxybenzene 
• 1186304-33-5 C₃₉H₄₂O₈ 
• 1186304-34-6 C₃₁H₃₀O₆ 
• 1186304-42-6 C₃₉H₄₄O₈ 
• 1366641-92-0 Br^(1-)*C₄₉H₄₄O₅P⁽¹⁺⁾ 

Relevant articles and documents

Palladium-Catalzyed Atroposelective 16-Membered Macrocyclization: Total Synthesis of Isoplagiochin D?

Isoplagiochin D is a ring-strained macrocyclic bisbibenzylis, which showed stable axial chirality in one biaryl structure, and semistable axial chirality in the other biaryl moiety. We reported here an unprecedented example for the catalytically asymmetri

Vanadium-Catalyzed Oxidative Intramolecular Coupling of Tethered Phenols: Formation of Phenol-Dienone Products

A mild and efficient method for the vanadium-catalyzed intramolecular coupling of tethered free phenols is described. The corresponding phenol-dienone products are prepared directly in good yields with low catalyst loadings. Electronically diverse tethered phenol precursors are well tolerated, and the catalytic method was effectively applied as the key step in syntheses of three natural products and a synthetically useful morphinan alkaloid precursor.

COMPOUNDS AND THEIR METHODS OF USE

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persis