1186304-33-5Relevant academic research and scientific papers
Design, synthesis and biological evaluation of nitrogen-containing macrocyclic bisbibenzyl derivatives as potent anticancer agents by targeting the lysosome
Sun, Bin,Liu, Jun,Gao, Yun,Zheng, Hong-bo,Li, Lin,Hu, Qing-wen,Yuan, Hui-qing,Lou, Hong-xiang
, p. 603 - 618 (2017)
A series of novel nitrogen-containing macrocyclic bisbibenzyl derivatives was designed, synthesized, and evaluated for antiproliferative activity against three anthropic cancer cell lines. Among these novel molecules, the tri-O-alkylated compound 18a disp
Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents
Jiang, Juan,Sun, Bin,Wang, Yan-Yan,Cui, Min,Zhang, Li,Cui, Chang-Zhi,Wang, Yan-Feng,Liu, Xi-Gong,Lou, Hong-Xiang
scheme or table, p. 2382 - 2391 (2012/05/05)
Based on the core skeleton of the total synthesized bisbibenzyl marchantin C, riccardin D and plagiochin E, a series of brominated and aminomethylated derivatives of above three bisbibenzyls have been synthesized and their cytotoxic activity against KB, M
Syntheses of macrocyclic bis(bibenzyl) compounds derived from perrottetin e
Speicher, Andreas,Groh, Matthias,Hennrich, Markus,Huynh, Anh-Minh
experimental part, p. 6760 - 6778 (2011/03/18)
Macrocyclic bis(bibenzyl) compounds are natural products from liverworts and are of growing interest due to recent reports on new isolated compounds and on their remarkable biological activities. We report here on a flexible and general approach to the to
A synthesis-driven structure revision of 'plagiochin E', a highly bioactive bisbibenzyl
Speicher, Andreas,Groh, Matthias,Zapp, Josef,Schauml?ffel, Anu,Knauer, Michael,Bringmann, Gerhard
scheme or table, p. 1852 - 1858 (2009/12/05)
Recently, a bisbibenzyl named plagiochin E showing remarkable antifungal and antitumor activities was isolated from Marchantia polymorpha, a liverwort. The total synthesis of the proposed structure for plagiochin E and of two structurally and biosynthetic
