171007-19-5

Basic information

• Product Name: 3-(3'-indolyl)-(2S)-(N-methylamino)-1,1-di(2''-methylphenyl)-1-propanol
• Synonyms: 3-(3'-indolyl)-(2S)-(N-methylamino)-1,1-di(2''-methylphenyl)-1-propanol
• CAS NO: 171007-19-5
• Molecular Weight: 384.521
• Mol File: 171007-19-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3'-indolyl)-(2S)-(N-methylamino)-1,1-di(2''-methylphenyl)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3'-indolyl)-(2S)-(N-methylamino)-1,1-di(2''-methylphenyl)-1-propanol(171007-19-5)
• EPA Substance Registry System: 3-(3'-indolyl)-(2S)-(N-methylamino)-1,1-di(2''-methylphenyl)-1-propanol(171007-19-5)

Safety Data

• Hazardous Substances Data: 171007-19-5(Hazardous Substances Data)

Upstream product

• 526-31-8 L-abrine 
• 932-31-0 ortho-tolylmagnesium bromide 
• 32164-04-8 (S)-(+)-N_b-methyltryptophan methyl ester 

Relevant articles and documents

Chiral ligands derived from abrine. 1. Synthesis of sec- and tert-β-amino alcohols and catalysis for enantioselective addition of diethylzinc toward aromatic aldehydes

A number of indole-containing chiral β-amino alcohols 3a-d and 9a-e have been synthesized from the alkaloid, Abrine (1) readily available from seeds of Abrus precatorius collected in Yunnan Province of China. Catalysis of the synthesized chiral ligands for the addition of diethylzinc toward benzaldehyde was examined. A significant role of the substituent(s) in the catalyst on the degree of asymmetric induction was uncovered. Enantiomeric excess of the product up to 94.2% was recorded.