171038-92-9

Upstream product

• 169217-35-0 (2R,3R,3'R)-3-hydroxy-2-(3'-hydroxy-15'-methylhexadecanoylamino)-15-methyl-hexadecan-1-sulfonic acid 
• 170242-21-4 (2R,3R)-3-Hydroxy-2-(13'-methyltetradecanoylamino)-15-methylhexadecanesulfonic acid 
• 67-56-1 methanol 
• 609340-81-0 3-tert-butyl 4-methyl (4R,5R)-2,2-dimethyl-5-(12-methyl-tridecyl)-1,3-oxazolidine-3,4-dicarboxylate 
• 609340-80-9 methyl (2R,3R)-2-(N-tert-butoxycarbonyl)amino-3-hydroxy-15-methyl-hexadecanoate 
• 609340-82-1 tert-butyl (4S,5R)-4-hydroxymethyl-2,2-dimethyl-5-(12-methyl-tridecyl)-1,3-oxazolidine-3-carboxylate 
• 736172-57-9 (2R,3R)-2-Amino-3-hydroxy-15-methyl-hexadecanoic acid methyl ester 
• 609340-83-2 tert-butyl (4R,5R)-4-acetylthiomethyl-2,2-dimethyl-5-(12-methyl-tridecyl)-1,3-oxazolidine-3-carboxylate 

Downstream Products

• 171038-94-1 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-1-((R)-1-tert-butoxycarbonylamino-2-sulfo-ethyl)-13-methyl-tetradecyl ester 
• 170964-42-8 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-1-((R)-1-tert-butoxycarbonylamino-2-sulfo-ethyl)-13-methyl-tetradecyl ester 
• 171038-97-4 (2R,3R)-3-Hydroxy-15-methyl-2-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-hexadecane-1-sulfonic acid 
• 170964-45-1 (2R,3R)-3-Hydroxy-15-methyl-2-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-hexadecane-1-sulfonic acid 
• 171038-96-3 (S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-13-methyl-1-[(R)-2-sulfo-1-((S)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-ethyl]-tetradecyl ester 
• 170964-44-0 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-13-methyl-1-[(R)-2-sulfo-1-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-ethyl]-tetradecyl ester 

Relevant academic research and scientific papers

Total synthesis of sulfobacin A through dynamic kinetic resolution of a racemic β-keto-α-amino ester hydrochloride

A total synthesis of sulfobacin A, a von Willebrand factor receptor antagonist, is described. Our synthetic approach relies uniquely on catalytic asymmetric reactions for the creation of the three stereogenic centers without using chiral building blocks.

A short total synthesis of sulfobacin A

A total synthesis of the von Willebrand factor receptor antagonist sulfobacin A is described. Key steps for this short route to sulfobacin A include ruthenium-catalyzed asymmetric hydrogenation and diastereoselective electrophilic amination for the construction of the three stereogenic centers.

Sulfobacins A and B, novel von Willebrand factor receptor antagonists. II. Structural elucidation

Sulfobacins A and B are novel von Willebrand factor (vWF) receptor antagonists produced by Chryseobacterium sp. NR 2993. The structures of sulfobacins A and B have been determined to be (2R,3R)-3-hydroxy-2-[(R)-3-hydroxy-15-methylhexadecanamido]-15- methylhexadecanesulfonic acid and (2R,3R)-3-hydroxy-15-methyl-2-[13-methyltetradecanamido]- hexadecanesulfonic acid, respectively, by various 2D NMR experiments and by methanolysis. The absolute configurations of the sulfobacins were determined by a modified MOSHER's method. The structures are related to sulfonolipids, major components of the cell envelope of gliding bacteria of the genus Cytophaga.