171190-03-7

Upstream product

• 644981-57-7 tri-tert-butyl [1S,1-(4S,5R),3S,4S,5R,6R,7R]-1-(4-acetoxy-5-methyl-6-phenyl-2-hexenyl)-6-benzyloxy-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 644981-59-9 (3R,4R)-4-methyl-5-phenyl-1-penten-3-yl acetate 
• 925453-63-0 (3R,4R)-4-methyl-5-phenyl-1-penten-3-ol 
• 219607-74-6 (2S,3R)-1,2-epoxy-3-methyl-4-phenylbutane 
• 925453-75-4 tri-tert-butyl [1S,1(3S,4S,5R),3S,4S,5R,6R,7R]-6-acetoxy-1-[4-acetoxy-5-methyl-3-[(2-nitrophenylseleno)methyl]-6-phenylhexyl]-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-69-6 tri-tert-butyl [1S,1(2E,4S,5R),3S,4S,5R,6R,7R]-6-benzyloxy-1-[4-[(bromomethyl)dimethylsilyl]oxy-5-methyl-6-phenyl-2-hexenyl]-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-74-3 tri-tert-butyl [1S,1(3S,4S,5R),3S,4S,5R,6R,7R]-7-(tert-butoxycarbonyl)oxy-4,6-dihydroxy-1-[4-hydroxy-5-methyl-3-[(2-nitrophenylseleno)methyl]-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-70-9 6-benzyloxy-7-tert-butoxycarbonyloxy-1-{2-[2,2-dimethyl-5-(1-methyl-2-phenyl-ethyl)-[1,2]oxasilolan-4-yl]-ethyl}-4-hydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester 
• 925453-71-0 tri-tert-butyl [1S,1(3R,4S,5R),3S,4S,5R,6R,7R]-6-benzyloxy-7-(tert-butoxycarbonyl)oxy-4-hydroxy-1-[4-hydroxy-3-(hydroxymethyl)-5-methyl-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-73-2 tri-tert-butyl [1S,1(3R,4S,5R),3S,4S,5R,6R,7R]-7-(tert-butoxycarbonyl)oxy-4,6-dihydroxy-1-[4-hydroxy-3-(hydroxymethyl)-5-methyl-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-76-5 tri-tert-butyl [1S,1(4S,5R),3S,4S,5R,6R,7R]-6-acetoxy-1-(4-acetoxy-5-methyl-3-methylene-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 

Downstream Products

• 925453-77-6 tri-tert-butyl [1S,1(4S,5R),3S,4S,5R,6R,6(2E,4S,6S),7R]-1-(4-acetoxy-5-methyl-3-methylene-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-6-(4,6-dimethyl-2-octenoyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 138682-84-5 zaragozic acid A 

Relevant academic research and scientific papers

Total syntheses of zaragozic acids A and C by a carbonyl ylide cycloaddition strategy

A carbonyl ylide cycloaddition approach to the squalene synthase inhibitors zaragozic acids A and C is described. The carbonyl ylide precursor 8 was synthesized starting from di-tert-butyl D-tartrate (47) via an eleven-step sequence involving the regiosel