219607-74-6

Upstream product

• 219607-73-5 (2R,3R)-2-(methanesulfonyl)oxy-3-methyl-4-phenyl-1-butanol 
• 219607-72-4 (2R,3R)-2-(methanesulfonyl)oxy-1-(4-methoxybenzyl)oxy-3-methyl-4-phenylbutane 
• 219607-71-3 (2R,3R)-1-(4-methoxybenzyl)oxy-3-methyl-4-phenyl-2-butanol 
• 219607-70-2 (2S,3S)-2,3-epoxy-1-(4-methoxybenzyl)oxy-4-phenylbutane 
• 78571-81-0 (2S-trans)-3-(Phenylmethyl)oxiranemethanol 
• 42238-15-3 (2E)-4-phenylbut-2-en-1-ol 

Downstream Products

• 219607-75-7 (2R,3R)-2-methyl-1-phenyl-5-hexyn-3-ol 
• 925453-63-0 (3R,4R)-4-methyl-5-phenyl-1-penten-3-ol 
• 164118-40-5 (2S,3R)-2-<(4-Methoxyphenyl)methoxy>-3-methyl-4-phenylbutanal 
• 644981-57-7 tri-tert-butyl [1S,1-(4S,5R),3S,4S,5R,6R,7R]-1-(4-acetoxy-5-methyl-6-phenyl-2-hexenyl)-6-benzyloxy-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 644981-59-9 (3R,4R)-4-methyl-5-phenyl-1-penten-3-yl acetate 
• 138682-84-5 zaragozic acid A 
• 925453-77-6 tri-tert-butyl [1S,1(4S,5R),3S,4S,5R,6R,6(2E,4S,6S),7R]-1-(4-acetoxy-5-methyl-3-methylene-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-6-(4,6-dimethyl-2-octenoyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-75-4 tri-tert-butyl [1S,1(3S,4S,5R),3S,4S,5R,6R,7R]-6-acetoxy-1-[4-acetoxy-5-methyl-3-[(2-nitrophenylseleno)methyl]-6-phenylhexyl]-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-69-6 tri-tert-butyl [1S,1(2E,4S,5R),3S,4S,5R,6R,7R]-6-benzyloxy-1-[4-[(bromomethyl)dimethylsilyl]oxy-5-methyl-6-phenyl-2-hexenyl]-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-74-3 tri-tert-butyl [1S,1(3S,4S,5R),3S,4S,5R,6R,7R]-7-(tert-butoxycarbonyl)oxy-4,6-dihydroxy-1-[4-hydroxy-5-methyl-3-[(2-nitrophenylseleno)methyl]-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-70-9 6-benzyloxy-7-tert-butoxycarbonyloxy-1-{2-[2,2-dimethyl-5-(1-methyl-2-phenyl-ethyl)-[1,2]oxasilolan-4-yl]-ethyl}-4-hydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester 
• 925453-71-0 tri-tert-butyl [1S,1(3R,4S,5R),3S,4S,5R,6R,7R]-6-benzyloxy-7-(tert-butoxycarbonyl)oxy-4-hydroxy-1-[4-hydroxy-3-(hydroxymethyl)-5-methyl-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 925453-76-5 tri-tert-butyl [1S,1(4S,5R),3S,4S,5R,6R,7R]-6-acetoxy-1-(4-acetoxy-5-methyl-3-methylene-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 
• 171190-03-7 tri-tert-butyl [1S,1(4S,5R),3S,4S,5R,6R,7R]-1-(4-acetoxy-5-methyl-3-methylene-6-phenylhexyl)-7-(tert-butoxycarbonyl)oxy-4,6-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylate 

Relevant academic research and scientific papers

Total Synthesis of the Squalene Synthase Inhibitor Zaragozic Acid C by a Carbonyl Ylide Cycloaddition Strategy

Ketal isomers avoided. The unique 2,8-dioxabicyclo[3.2.1 ]octane core of zaragozic acid C (1) was constructed in a Rh-catalyzed 1,3-dipolar cycloaddition of an alkyne to an ester carbonyl ylide. Another feature of this improved synthesis is the constructi

Facile and efficient preparation of a C-1 side chain equivalent of zaragozic acid C

An optically pure C-1 side chain equivalent of zaragozic acid C, (4R,5R)-4-benzyloxy-5-methyl-6-phenyl-1-hexyne, has been synthesized in ten steps from (E)-4-phenyl-2-buten-1-ol with an overall yield of 50%, involving a Sharpless asymmetric epoxidation as