171190-55-9Relevant academic research and scientific papers
Cascade radical cyclisations of imines
Bowman, W. Russell,Stephenson, Peter T.,Young, Adrian R.
, p. 11445 - 11462 (2007/10/03)
Cascade radical reactions, initiated by cyclisation of sp3 carbon-centred radicals onto the C-atom of imines, have been used to develop a new protocol for the synthesis of a range of nitrogen heterocycles. The C-centred radical intermediates were generated from benzeneselenyl precursors using Bu3SnH. The aminyl radicals generated by cyclisation onto imines undergo further 5- or 6-exo cyclisation with suitably placed alkenes.
