171227-49-9

Basic information

• Product Name: (1R,1'R)-N-(2'-methoxy-1'-phenylethyl)-1,2-dimethylpropylamine
• Synonyms: (1R,1'R)-N-(2'-methoxy-1'-phenylethyl)-1,2-dimethylpropylamine
• CAS NO: 171227-49-9
• Molecular Weight: 221.343
• Mol File: 171227-49-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R,1'R)-N-(2'-methoxy-1'-phenylethyl)-1,2-dimethylpropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,1'R)-N-(2'-methoxy-1'-phenylethyl)-1,2-dimethylpropylamine(171227-49-9)
• EPA Substance Registry System: (1R,1'R)-N-(2'-methoxy-1'-phenylethyl)-1,2-dimethylpropylamine(171227-49-9)

Safety Data

• Hazardous Substances Data: 171227-49-9(Hazardous Substances Data)

Upstream product

• 205690-63-7 (2R,4R)-3-diphenylmethyl-2-methyl-4-phenyl-1,3-oxazolidine 
• 205690-68-2 (R)-2-[Benzhydryl-((R)-1,2-dimethyl-propyl)-amino]-2-phenyl-ethanol 
• 167280-31-1 (R)-2-diphenylmethylamino-2-phenylethanol 
• 167280-30-0 (R)-2-diphenylmethylideneamino-2-phenylethanol 
• 56613-80-0 D-2-phenylglycinol 
• 172488-14-1 ((R)-2-Methoxy-1-phenyl-ethyl)-[2-methyl-prop-(E)-ylidene]-amine 
• 64715-85-1 (R)-2-methoxy-1-phenylethylamine 
• 514168-48-0 (S)-2-Isopropyl-1-((R)-2-methoxy-1-phenyl-ethyl)-aziridine 
• 75-16-1 methylmagnesium bromide 
• 159116-87-7 (R)-2-methoxy-N-(2-methylpropylidene)-1-phenylethylamine 

Downstream Products

• 598-74-3 (2R)-3-methyl-2-butylamine 

Relevant articles and documents

Facile asymmetric synthesis of aziridine derivatives via the diastereoselective reaction of chiral imines with dimethylsulfonium methylide

A simple method for the synthesis of chiral 2-substituted aziridine derivatives is described. The reaction pathway consists of the diastereoselective addition of dimethylsulfonium methylide to chiral imines derived from (R)-phenylglycinol and various aldehydes.

Diastereoselective addition of chiral aliphatic imines and 2-alkyl-1,3-oxazolidines to organometallic reagents

The reaction of organocerium reagents with chiral aliphatic imines derived from (R)-O-methylphenylglycinol afforded the corresponding amines with high diastereoselectivity. In contrast, the reaction of Grignard reagents with chiral 2-alkyl-1,3-oxazolidines derived from (R)-N-methylphenylglycinol afforded the amines with changeover in diastereoselectivity.