171257-01-5Relevant articles and documents
Method for preparing beixifloxacin intermediate compound
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Paragraph 0100; 0101; 0102; 0103; 0104; 0105; 0106, (2018/03/01)
The invention provides a method for preparing a beixifloxacin intermediate compound VI. The method comprises the steps of: reacting a compound of a formula III with an upper protective group, an aminotransferase catalying and a deprotecting group to obtain a compound shown in a formula VI. The method can be used for preparing the beixifloxacin intermediate compound VI rapidly and effectively. Rawmaterials are simple and easy to obtain, the reaction is simple and easy to operate, harsh reaction conditions are not required, a production period is short, yield of a target product is high, separation and purification of the target product are simple, optical purity is high, the method is easy to achieve mass production.
NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS
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Page/Page column 87, (2008/06/13)
The present invention relates to compounds of general formula (I) wherein the groups and radicals B, k, L, U,V, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH- receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.