171268-85-2

Basic information

• Product Name: C₃₇H₄₆N₂O₈Si
• Synonyms: C₃₇H₄₆N₂O₈Si
• CAS NO: 171268-85-2
• Molecular Weight: 674.866
• Mol File: 171268-85-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₇H₄₆N₂O₈Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₇H₄₆N₂O₈Si(171268-85-2)
• EPA Substance Registry System: C₃₇H₄₆N₂O₈Si(171268-85-2)

Safety Data

• Hazardous Substances Data: 171268-85-2(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 103285-22-9 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine 

Downstream Products

• 171268-84-1 1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

Regulating angiogenesis with light-inducible antimirs

The inhibition of microRNAs (miRs) in a spatiotemporally defined manner by an exogenous trigger would help to specifically target the biological activity and avoid off-target effects. Novel antimiRs directed against miR-92a can be activated by irradiation (see scheme; 3′-UTR=3′-untranslated region) In this way miR-92a is inhibited, the miR-92a target integrin α5 is derepressed, and angiogenesis of endothelial cells is enhanced. Copyright

Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides

Hepatitis C virus afflicts approximately 180 million people worldwide and currently there are no direct acting antiviral agents available to treat this disease. Our first generation nucleoside HCV inhibitor, RG7128 has already established proof-of-concept