17127-83-2 Usage
Uses
Used in Pharmaceutical Synthesis:
3-Amino-2-bromoquinoline is used as a building block for the production of various biologically active molecules. Its unique structure and properties make it a valuable component in the creation of new pharmaceuticals with potential therapeutic applications.
Used in Organic Synthesis:
As a reagent, 3-amino-2-bromoquinoline is utilized in organic synthesis processes, contributing to the development of a wide range of organic compounds with diverse applications.
Used in Medicinal Chemistry and Drug Discovery:
3-Amino-2-bromoquinoline has potential applications in the field of medicinal chemistry, where it can be employed in the design and synthesis of new drug candidates. Its presence in the development pipeline can lead to the discovery of innovative treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 17127-83-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,2 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17127-83:
(7*1)+(6*7)+(5*1)+(4*2)+(3*7)+(2*8)+(1*3)=102
102 % 10 = 2
So 17127-83-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrN2/c10-9-7(11)5-6-3-1-2-4-8(6)12-9/h1-5H,11H2
17127-83-2Relevant academic research and scientific papers
Regioselective one-pot bromination of aromatic amines
Smith, Michael B.,Guo, Lisa,Okeyo, Sherrad,Stenzel, Jason,Yanella, James,LaChapelle, Eric
, p. 2321 - 2323 (2007/10/03)
(Matrix Presented) Treatment of aniline with n-butyllithium and then trimethyltin chloride gave the tin amide (PhNH-SnMe3) in situ. Without isolation of the tin amide reaction with bromine and workup with aqueous fluoride ion gave p-bromoaniline in 76% yield, with no dibromoaniline or o-bromoaniline. Application of this sequence to 11 different aromatic amines gave selective bromination in 36-91% yields, without formation of dibromides. This constitutes a good general method for the regioselective bromination of aromatic amines.
