1713-83-3Relevant academic research and scientific papers
LaCl3·7H2O-promoted regioselective ring opening of epoxides using NaNO2 in ether-water system: A facile synthesis of 2-nitroalcohols
Borah, Jagat C.,Gogoi, Siddhartha,Boruwa, Joshodeep,Barua, Nabin C.
, p. 873 - 878 (2007/10/03)
A convenient and efficient synthesis of 2-nitroalcohols has been achieved by regioselective ring opening of epoxides using LaCl3·7H 2O and NaNO2 in ether-H2O system at room temperature. The reaction afforded the corresponding products in good to excellent yields under mild conditions.
Synthesis of 2-nitroalcohols by regioselective ring opening of epoxides with MgSO4/MeOH/NaNO2 system: A short synthesis of immunosuppressive agent FTY-720
Kalita,Barua,Bezbarua,Bez
, p. 1411 - 1414 (2007/10/03)
It has been demonstrated that a variety of epoxides can easily be opened with a system consisting of MgSO4/MeOH/NaNO2 giving the corresponding 2-nitroalcohols in excellent yields. This strategy has been applied to achieve a short synthesis of Immunosuppressive Agent FTY - 720.
2-Amino-2-deoxytetrose derivatives. Preparation from 4,5-dihydroisoxazoles via reductive cleavage
Wade,D'Ambrosio,Price
, p. 6302 - 6308 (2007/10/03)
The 4-alkoxy-3-nitro-4,5-dihydroisoxazoles 2a,b were prepared by condensation of nitromethane and chloroacetaldehyde, protection of the resulting nitroaldol 1c, and subsequent nitrosative cyclization. Multistep replacement of the nitrogroup of 2a,b by a 2
