17133-95-8

Usage

Uses

Used in Food Industry:
2-Ethyl-5-methylbenzofuran is used as a flavoring agent for its pleasant, vanilla-like odor, adding a distinct fragrance to various food products.
Used in Pharmaceutical Applications:
Leveraging its antioxidant and antimicrobial properties, 2-Ethyl-5-methylbenzofuran serves as an active ingredient in pharmaceutical formulations, contributing to the preservation and efficacy of medicated products.
Used in Food Preservation:
The antimicrobial properties of 2-Ethyl-5-methylbenzofuran make it useful in food preservation, helping to extend the shelf life of food items by inhibiting the growth of spoilage-causing microorganisms.
Used in Antioxidant Formulations:
As an antioxidant, 2-Ethyl-5-methylbenzofuran is used in formulations to protect against oxidative stress, which can be beneficial in both food and pharmaceutical applications.
Used in Neurological Disorder Treatment Research:
2-Ethyl-5-methylbenzofuran is studied for its potential as a therapeutic agent in the treatment of neurological disorders, indicating a future application in the medical field for managing such conditions.

InChI:InChI=1/C11H12O/c1-3-10-7-9-6-8(2)4-5-11(9)12-10/h4-7H,3H2,1-2H3

Upstream product

• 41389-28-0 2-Crotyl-4-methyl-phenol 
• 106-44-5 p-cresol 
• 66614-56-0 1-(2,2-diethoxyethoxy)-4-methylbenzene 
• 18441-43-5 5-methylbenzofuran 
• 74-96-4 ethyl bromide 

Downstream Products

• 70049-65-9 2-Ethyl-3-(4-chloro-3-sulfamoylbenzoyl)-5-methyl-benzo[b]furan 

Relevant academic research and scientific papers

Enantio- and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis

We report an enantio- and diastereoselective, complete hydrogenation of multiply substituted benzofurans in a one-pot cascade catalysis. The developed protocol facilitates the controlled installation of up to six new defined stereocenters and produces architecturally complex octahydrobenzofurans, prevalent in many bioactive molecules. A unique match of a chiral homogeneous ruthenium-N-heterocyclic carbene complex and an in situ activated rhodium catalyst from a complex precursor act in sequence to enable the presented process.

cis-Oxypalladation Complexes Derived from (1R,5R)-2(10),3-Pinadiene and Their Utilization in Pd(II)-catalyzed Enantioselective Cyclization of 2-(trans-2-Butenyl)phenols

(1R,5R)-2(10),3-Pinadiene, when treated with either Na2PdCl4 in MeOH or Pd(OAc)2 in AcOH and NaCl, gives di-μ-chloro-bis (4a) or (4b), respectively.These complexes represent the firstly isolated cis-oxypalladation adduct.The ligand exchange of 4b with AgOAc affords di-μ-acetato-bis (5b) which serves as the catalyst for the asymmetric cyclization of 2-(trans-2-butenyl)phenols leading to 2-vinyl-2,3-dihydrobenzofurans (13).Although the enantioselectivities induced in this asymmetric cyclization are not high (1-29percent ee), noteworthy is that the cis-complex 5b affords (R)-(-)-enantiomer of 13 while the parent di-μ-acetato-bis give the (S)-isomer.As an application of the present asymmetric cyclization, attempts to synthesize (S)-(+)-tremetone have been made.