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L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide, also known as Leu-Val hydrazide, is a synthetic compound with potential anticancer and chemopreventive activities. It is a selective inhibitor of the proteasome, an enzyme complex that degrades unwanted proteins in cells, and has been shown to induce apoptosis in cancer cells.

17137-03-0

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17137-03-0 Usage

Uses

Used in Cancer Treatment Applications:
L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide is used as a potential anticancer agent for its ability to selectively inhibit the proteasome, leading to the induction of apoptosis in cancer cells. It has been studied for its potential in treating various types of cancer, including breast and prostate cancer, and has shown promise in preclinical studies.
Used in Combination Therapies:
L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide is used as a potential component in combination therapies with other cancer treatments. It is being investigated for its potential to enhance the effectiveness of existing cancer treatments and improve patient outcomes.
Used in Cancer Research:
L-Leucine, N-[N-[(phenylmethoxy)carbonyl]-L-valyl]-, hydrazide is used as a subject of study in cancer research to further understand its mechanisms of action and potential applications in cancer treatment. This research may lead to the development of new therapeutic strategies and clinical applications in the future.

Check Digit Verification of cas no

The CAS Registry Mumber 17137-03-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,3 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17137-03:
(7*1)+(6*7)+(5*1)+(4*3)+(3*7)+(2*0)+(1*3)=90
90 % 10 = 0
So 17137-03-0 is a valid CAS Registry Number.

17137-03-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-Val-Leu-NHNH2

1.2 Other means of identification

Product number -
Other names [(S)-1-((S)-1-Hydrazinocarbonyl-3-methyl-butylcarbamoyl)-2-methyl-propyl]-carbamic acid benzyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17137-03-0 SDS

17137-03-0Downstream Products

17137-03-0Relevant academic research and scientific papers

Synthesis of Substrates of Cyclic AMP-dependent Protein Kinase and Use of Their Protected Precursors for the Convenient Preparation of Phosphoserine Peptides

Grehn, Leif,Fransson, Bengt,Ragnarsson, Ulf

, p. 529 - 536 (2007/10/02)

The synthesis of protected hexa- to nona-peptide precursors of substrates of cycylic AMP-dependent protein kinase, based on a partial amino acid sequence from rat liver pyruvate kinase, as well as of related phosphoserine peptides has been explored.A conv

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