17138-39-5

Upstream product

• 126523-21-5 1-[2-(4-Benzyloxy-2-bromo-5-methoxy-phenyl)-ethyl]-5,6-dimethoxy-1H-indole 
• 47706-26-3 7-benzyloxy-1-(2-bromo-4,5-dimethoxybenzyl)-1,2,3,4-tetrahydro-6-methoxyisoquinoline 
• 58446-74-5 7-benzyloxy-1-(2-bromo-4,5-dimethoxy-benzyl)-6-methoxy-3,4-dihydro-isoquinoline 
• 54313-35-8 2-(4-(benzyloxy)-3-methoxyphenyl)acetyl chloride 
• 83392-71-6 <(3,4-dimethoxyphenyl)methyl>trimethylsilane 
• 71924-62-4 2-fluoro-4,5-dimethoxybenzaldehyde 
• 15357-95-6 7-(benzyloxy)-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1361538-08-0 N-(2-(7-(benzyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dimethoxybenzylidene)-2-phenylaziridin-1-amine 
• 1361537-93-0 2-(7-(benzyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-4,5-dimethoxybenzaldehyde 
• 64434-31-7 2-bromo-4-benzyloxy-5-methoxyphenylacetic acid 
• 112462-81-4 N-[2-(4-Benzyloxy-3-methoxy-phenyl)-ethyl]-N-(4,5-dimethoxy-2-trimethylsilanylmethyl-phenyl)-formamide 
• 112462-79-0 2-(4-Benzyloxy-3-methoxy-phenyl)-N-(4,5-dimethoxy-2-trimethylsilanylmethyl-phenyl)-acetamide 
• 112462-80-3 [2-(4-Benzyloxy-3-methoxy-phenyl)-ethyl]-(4,5-dimethoxy-2-trimethylsilanylmethyl-phenyl)-amine 
• 112487-73-7 (4,5-Dimethoxy-2-nitro-benzyl)-trimethyl-silane 

Downstream Products

• 17389-24-1 (+/-)-O-benzylcryptaustoline 
• 126523-22-6 2,2'-Bis-benzyloxy-3,9,10,3',9',10'-hexamethoxy-5,6,5',6'-tetrahydro-[12,12']bi[indolo[2,1-a]isoquinolinyl] 

Relevant academic research and scientific papers

N-fused indolines through non-carbonyl-stabilized rhodium carbenoid C-H insertion of N-aziridinyl imines

Under rhodium catalysis, N-aziridinyl imines provided access to N-fused indolines through non-carbonyl-stabilized rhodium carbenoid C-H insertion. The utility of this methodology for the synthesis of architecturally complex heterocycles was further demonstrated by an expedient total synthesis of ( ±)-cryptaustoline (see scheme). Copyright

Use of (NHC)Pd(η3-allyl)Cl (NHC = N-Heterocyclic Carbene) in a Palladium-mediated Approach to Cryptocarya Alkaloids

The palladium-mediated intramolecular aryl amination of 7-benzyloxy-1-(2-bromo-4,5-dimethoxy-benzyl)-1,2,3, 4-tetrahydro-6-methoxy-isoquinoline catalyzed by a recently discovered, air and moisture stable (NHC)Pd(η3-allyl)Cl (NHC = N-heterocycli

A facile route to indolo[2,1-a]isoquinolines and dibenzopyrrocoline alkaloids

(Formula presented) Treatment of 1-(2′-bromobenzyl)-3,4-dihydroisoquinolines 2 in the presence of K2CO3 in boiling DMF efficiently provided a variety of alkoxysubstituted indolo[2,1-a]isoquinolines 3. Application of this cyclization

A NOVEL TOTAL SYNTHESIS OF (+/-)-CRYPTAUSTOLINE, A DIBENZOPYRROCOLINE ALKALOID

(+/-)-Cryptaustoline (1), a dibenzopyrrocoline alkaloid, was efficiently synthesized from the readily available N-phenethylaniline (7) via the N-phenethyloxindole (12) or the N-phenethylindole (14) by the Bischler-Napieralski reaction or by radical cycliz

SILICON-MEDIATED ISOQUINOLINE ALKALOID SYNTHESIS: A NEW ROUTE TO THE DIBENZOPYRROCOLINE ALKALOID (+/-)-CRYPTAUSTOLINE

A fundamentally new synthesis of the benzopyrrocoline alkaloid (+/-)-cryptaustoline iodide (12) has been devised by employing the silicon mediated ring closure through a formal 5-Endo-Trigonal process.